Checkpoint Blockade–Induced Dermatitis and Colitis Are Dominated by Tissue-Resident Memory T Cells and Th1/Tc1 Cytokines
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-22-0362
Abstract: Greater understanding of immune-related adverse events (irAE) could lead to new approaches in overcoming them. The authors show immunopathology of irAE dermatitis is dominated by Th1/Tc1 TRM cells, suggesting topical JAK inhibitors as corticosteroid-sparing agents… read more here.
Keywords: blockade induced; induced dermatitis; th1 tc1; dermatitis colitis ... See more keywords
Effects of age on sugammadex reversal of neuromuscular blockade induced by rocuronium in Chinese children: a prospective pilot trial
Sign Up to like & getrecommendations! Published in 2021 at "BMC Anesthesiology"
DOI: 10.1186/s12871-021-01465-9
Abstract: Background Sugammadex reverses neuromuscular blockade induced by steroidal relaxants. We compared the recovery for neuromuscular blockade reversal with sugammadex in children aged 1–12 years. Methods From August 2019 to August 2020, patients who received 2.0 mg·kg − 1… read more here.
Keywords: reversal; trial; sugammadex; neuromuscular blockade ... See more keywords