Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-018-1276-4
Abstract: BackgroundVery late antigen 4 (VLA-4; integrin α4β1) is critical for transmigration of T helper (TH) 1 cells into the central nervous system (CNS) under inflammatory conditions such as multiple sclerosis (MS). We have previously shown… read more here.
Keywords: choroid plexus; blockade mcam; migration; mcam ... See more keywords