Blockade of TMEM16A protects against renal fibrosis by reducing intracellular Cl- concentration.
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DOI: 10.1111/bph.15786
Abstract: BACKGROUND AND PURPOSE Renal fibrosis is the final common outcome in most forms of CKD. However, the underlying causal mechanisms remain obscure. The present study examined whether TMEM16A, a Ca2+ -activated chloride channel, contributes to… read more here.
Keywords: expression; renal fibrosis; blockade tmem16a; intracellular concentration ... See more keywords