Articles with "blocking autophagy" as a keyword



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Polystyrene exacerbates cadmium-induced mitochondrial damage to lung by blocking autophagy in mice.

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Published in 2023 at "Environmental toxicology"

DOI: 10.1002/tox.23804

Abstract: Cadmium (Cd) is an environmental heavy metal, and its accumulation is harmful to animal and human health. The cytotoxicity of Cd includes oxidative stress, apoptosis, and mitochondrial histopathological changes. Furthermore, polystyrene (PS) is a kind… read more here.

Keywords: damage; induced mitochondrial; blocking autophagy; lung ... See more keywords
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Blocking Autophagy in M1 Macrophages Enhances Virus Replication and Eye Disease in Ocularly Infected Transgenic Mice

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Published in 2022 at "Journal of Virology"

DOI: 10.1128/jvi.01401-22

Abstract: Autophagy plays a critical role in clearing, disassembling, and recycling damaged cells, thus limiting inflammation. The HSV-1 γ34.5 gene is involved in neurovirulence and immune evasion by blocking autophagy in infected cells. ABSTRACT Macrophages are… read more here.

Keywords: blocking autophagy; autophagy macrophages; eye; eye disease ... See more keywords