Articles with "blocking axis" as a keyword



Rational development of molecularly imprinted nanoparticles for blocking PD-1/PD-L1 axis

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Published in 2022 at "Chemical Science"

DOI: 10.1039/d2sc03412c

Abstract: Blocking the PD-1/PD-L1 immune checkpoint has emerged as a promising strategy in cancer immunotherapy, in which monoclonal antibodies are predominately used as inhibitors. Despite their remarkable success, monoclonal antibody-based therapeutics suffer from drawbacks due to… read more here.

Keywords: blocking axis; development molecularly; molecularly imprinted; rational development ... See more keywords

Blocking the IL-4/IL-13 Axis versus the JAK/STAT Pathway in Atopic Dermatitis: How Can We Choose?

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Published in 2024 at "Journal of Personalized Medicine"

DOI: 10.3390/jpm14070775

Abstract: Atopic dermatitis (AD) is an immune-mediated skin disorder with a chronic-relapsing course and a multifactorial pathogenesis. In contrast to the traditional concept of AD as solely a type 2 immune-activated disease, new findings highlight the… read more here.

Keywords: stat pathway; jak; blocking axis; atopic dermatitis ... See more keywords