Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation
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DOI: 10.7150/thno.32352
Abstract: Rationale: Renal fibrosis is the terminal manifestation of chronic and irreversible renal disease. Effective therapies other than dialysis are extremely limited. In this study, we investigated the potential effects of targeting elevated interleukin-6 (IL-6) levels… read more here.
Keywords: fibrosis; blocking interleukin; trans signaling; renal fibrosis ... See more keywords