Articles with "blocking smad" as a keyword



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CD82 attenuates TGF-β1-mediated epithelial-mesenchymal transition by blocking smad-dependent signaling in ARPE-19 cells

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.991056

Abstract: In retinal pigment epithelial (RPE) cells, transforming growth factor-beta (TGF-β) plays a critical role in epithelial-mesenchymal transition (EMT), which contributes to various fibrotic retinal disorders. In the present study, we investigated the effect of recombinant… read more here.

Keywords: mesenchymal transition; smad dependent; epithelial mesenchymal; arpe cells ... See more keywords