Fluorinated Cycloalkyl Building Blocks for Drug Discovery
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DOI: 10.1002/cmdc.202200365
Abstract: The review covers various aspects of fluorinated cycloalkyl (C3−C7) building blocks for drug discovery, including their synthesis, key physicochemical properties, and biological and medicinal applications of their derivatives. The discussed synthetic methods include classical nucleophilic… read more here.
Keywords: drug discovery; cycloalkyl building; blocks drug; building blocks ... See more keywords
Conjugated hydrophobic and hydrophilic blocks through a drug moiety as a leading macromolecular system for sustainable drug delivery
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DOI: 10.1007/s10965-020-02302-2
Abstract: Ring-opening polymerization (ROP) of ε-caprolactone (CL) had been performed at 160 °C in the presence of drug molecules such as penicillin g (Pen), streptavidin (Strep) and terramicin (Ter) as a lone chemical initiator using the… read more here.
Keywords: conjugated hydrophobic; hydrophilic blocks; blocks drug; drug ... See more keywords