Cell‐Derived Vesicles for Nanoparticles' Coating: Biomimetic Approaches for Enhanced Blood Circulation and Cancer Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201214
Abstract: Cancer nanomedicines are designed to encapsulate different therapeutic agents, prevent their premature release, and deliver them specifically to cancer cells, due to their ability to preferentially accumulate in tumor tissue. However, after intravenous administration, nanoparticles… read more here.
Keywords: derived vesicles; blood circulation; cancer; circulation ... See more keywords
Two-Dimensional Ultra-Thin Nanosheets with Extraordinarily High Drug Loading and Long Blood Circulation for Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200299
Abstract: Nanoparticle drug delivery is largely restricted by the low drug loading capacity of nanoparticle carriers. To address this critical challenge and maximize the potential of nanoparticle drug delivery, a 2D ultra-thin layered double hydroxide (LDH)… read more here.
Keywords: high drug; blood circulation; ultra thin; drug ... See more keywords
Cell-free DNA in blood circulation is generated by DNase1L3 and caspase-activated DNase.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.06.069
Abstract: Cell-free DNA (cfDNA) (e.g. fetal- or tumor-derived DNA) is DNA found in the blood circulation. It is now widely investigated as a biomarker for prenatal screening, tumor diagnosis, and tumor monitoring as "liquid biopsies". However,… read more here.
Keywords: dna; free dna; cell free; activated dnase ... See more keywords
Engineering long-circulating nanomaterial delivery systems.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2020.07.006
Abstract: One of the grand challenges at the forefront of bionanomaterials is their quick clearance in blood circulation. Progress has been made in understanding nanomaterial-biological system interactions and in developing new strategies to extend the blood… read more here.
Keywords: long circulating; engineering long; delivery systems; nanomaterial delivery ... See more keywords
Biosynthetic Mechanism of Luminescent ZnO Nanocrystals in the Mammalian Blood Circulation and Their Functionalization for Tumor Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b13691
Abstract: The biosynthesis of nanoparticles in bioreactors using microbial, plant, or animal cells is at the forefront of nanotechnology. We demonstrated for the first time that luminescent, water-soluble ZnO nanocrystals (bio-ZnO NCs) can be spontaneously biosynthesized… read more here.
Keywords: zno nanocrystals; blood circulation; mammalian blood; zno ... See more keywords
Elasticity of mesoporous nanocapsules regulates cellular uptake, blood circulation, and intratumoral distribution.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01701f
Abstract: The elasticity of nanoparticles plays a critical role in regulating nanoparticle-biosystem interactions. However, the elasticity of traditional organic-based carriers can only be regulated within a narrow range, and the effects of elasticity on in vivo… read more here.
Keywords: elasticity; elastic mons100; blood circulation; cellular uptake ... See more keywords
Stabilization of bicelles using metal-binding peptide for extended blood circulation.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc01058e
Abstract: A metal-binding peptide appending cholic acid, Chol-MBP, formed bicelles by mixing with 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine (DPPC). Coordination of Chol-MBP with Cu2+ stabilized DPPC bicelles against dilution and contamination of serum proteins, enabling extended blood circulation. This study… read more here.
Keywords: extended blood; metal binding; binding peptide; blood circulation ... See more keywords
Lymphatics - not just a chylomicron conduit
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Lipidology"
DOI: 10.1097/mol.0000000000000821
Abstract: Purpose of review Lymphatics are known to have active, regulated pumping by smooth muscle cells that enhance lymph flow, but whether active regulation of lymphatic pumping contributes significantly to the rate of appearance of chylomicrons… read more here.
Keywords: chylomicron conduit; lymphatics chylomicron; lymphatic pumping; blood circulation ... See more keywords
The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2021/9934107
Abstract: Objectives To determine whether feeding CircuCare to rats improves blood circulation, metabolism, immune regulation, endocrine activity, and oxidative stress. Methods 28 eight-week-old male Sprague-Dawley rats were evenly randomized into control and experimental groups. The control… read more here.
Keywords: blood circulation; circucare; circulation metabolism; metabolism ... See more keywords
The effect of zwitterionic surface content on blood circulation time of nanocapsule
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomaterials Applications"
DOI: 10.1177/0885328220935381
Abstract: Zwitterionic modification can prolong the blood circulation time of nanocarrier in vivo, but zwitterionic content will affect the functions of nanocarrier such as enzyme-responsive and intracellular or extracellular delivery. Therefore, it is necessary to explore… read more here.
Keywords: surface; content; circulation time; blood circulation ... See more keywords
Correlation between the range of motion of the tibiotarsal joint and blood circulation in the lower limbs in diabetic individuals.
Sign Up to like & getrecommendations! Published in 2022 at "Revista da Associacao Medica Brasileira"
DOI: 10.1590/1806-9282.20210961
Abstract: OBJECTIVE The aim of this study was to evaluate the relationship between the range of motion and lower-limb hemodynamic indices in the tibiotarsal joint of individuals with diabetic neuropathy. METHODS Twenty volunteers of both sexes,… read more here.
Keywords: range motion; blood; blood circulation; tibiotarsal joint ... See more keywords