Biosensing human blood clotting factor by dual probes: Evaluation by deep LSTM networks in time series forecasting.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2164
Abstract: Artificial intelligent of things (AIoT) has become a potential tool to be implemented in a wide range of fields and expanding with interdisciplinary sciences. On the other hand, in clinical scenario human blood clotting disease… read more here.
Keywords: lstm networks; time series; clotting factor; human blood ... See more keywords
Surface-Modified Melt Coextruded Nanofibers Enhance Blood Clotting in Vitro.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200292
Abstract: Blood loss causes an estimated 1.9 million deaths per year globally, making new methods to stop bleeding and promote clot formation immediately following injury paramount. The fabrication of functional hemostatic materials has the potential to… read more here.
Keywords: modified melt; surface modified; melt coextruded; blood ... See more keywords
Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis.
Sign Up to like & getrecommendations! Published in 2019 at "Immunity"
DOI: 10.1016/j.immuni.2019.04.003
Abstract: Inflammasome activation and subsequent pyroptosis are critical defense mechanisms against microbes. However, overactivation of inflammasome leads to death of the host. Although recent studies have uncovered the mechanism of pyroptosis following inflammasome activation, how pyroptotic… read more here.
Keywords: death; inflammasome activation; pyroptosis; host ... See more keywords
An adhesive and injectable nanocomposite hydrogel of thiolated gelatin/gelatin methacrylate/Laponite® as a potential surgical sealant.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2019.12.048
Abstract: Hemostatic adhesive hydrogels as sealants for surgical operations are one of the focus of the researches in the field of injectable materials. Herein, we evaluated the potential application of a mechanically robust nanocomposite hydrogel with… read more here.
Keywords: hydrogel; nanocomposite hydrogel; gelatin methacrylate; gelatin ... See more keywords
Proteins behaving badly. Substoichiometric molecular control and amplification of the initiation and nature of amyloid fibril formation: lessons from and for blood clotting.
Sign Up to like & getrecommendations! Published in 2017 at "Progress in biophysics and molecular biology"
DOI: 10.1016/j.pbiomolbio.2016.08.006
Abstract: The chief and largely terminal element of normal blood clotting is considered to involve the polymerisation of the mainly α-helical fibrinogen to fibrin, with a binding mechanism involving 'knobs and holes' but with otherwise little… read more here.
Keywords: proteins behaving; formation; fibrin; biology ... See more keywords
Engineered isopeptide bond stabilized fibrin inspired nanoscale peptide based sealants for efficient blood clotting
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-06360-3
Abstract: Designing biologically inspired nanoscale molecular assembly with desired functionality is a challenging endeavour. Here we report the designing of fibrin-inspired nanostructured peptide based sealants which facilitate remarkably fast entrapping of blood corpuscles (~28 seconds) in… read more here.
Keywords: peptide; fibrin inspired; blood; isopeptide bond ... See more keywords
Comparison of rotational thromboelastometry parameters with 20-minute whole blood clotting test as a predictor of envenoming in Russell's viper bite patients.
Sign Up to like & getrecommendations! Published in 2021 at "Transactions of the Royal Society of Tropical Medicine and Hygiene"
DOI: 10.1093/trstmh/trab052
Abstract: BACKGROUND Coagulopathy is an important and common systemic clinical syndrome caused by snake envenoming. The major clinical effect of Russell's viper (RV) envenoming is haematotoxicity. The 20-min whole blood clotting test (WBCT20) is the standard… read more here.
Keywords: clotting test; blood; test; russell viper ... See more keywords
Complementation of ELISA and an Interdigitated Electrode Surface in Gold Nanoparticle Functionalization for Effective Detection of Human Blood Clotting Defects
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale Research Letters"
DOI: 10.1186/s11671-019-3058-z
Abstract: Developing an enhanced diagnosis using biosensors is important for the treatment of patients before disease complications arise. Improving biosensors would enable the detection of various low-abundance disease biomarkers. Efficient immobilization of probes/receptors on the sensing… read more here.
Keywords: detection; elisa interdigitated; surface; human blood ... See more keywords
Efficacy of the 20-minute whole blood clotting test (WBCT20) in the diagnosis of coagulation alteration related to snakebites in a Western Brazilian Amazon hospital
Sign Up to like & getrecommendations! Published in 2021 at "Revista da Sociedade Brasileira de Medicina Tropical"
DOI: 10.1590/0037-8682-0091-2021
Abstract: Abstract Introduction: The efficacy of 20-minute whole blood clotting (WBCT20) and the Lee-White clotting time (LWCT) tests in diagnosing coagulation alterations from snakebites were compared. Methods: We evaluated 89 snakebite cases treated at the Hospital… read more here.
Keywords: coagulation; efficacy minute; minute whole; whole blood ... See more keywords
In vitro hemocompatability evaluation of gold nanoparticles capped with Lactobacillus plantarum derived lipase1.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical hemorheology and microcirculation"
DOI: 10.3233/ch-189117
Abstract: BACKGROUND Gold nanoparticles (GNPs) are key diagnostic and therapeutic agents in biomedical sciences. Several studies have been carried out in different therapeutic areas such as in cancer treatment, antibacterial topical agents, imaging agents etc. There… read more here.
Keywords: gold nanoparticles; nanoparticles capped; lipase; blood ... See more keywords