Characterization of blood coagulation dynamics and oxygenation in ex-vivo retinal vessels by fluorescence hyperspectral imaging (fHSI).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biophotonics"
DOI: 10.1002/jbio.202000021
Abstract: Blood coagulation mechanisms forming a blood clot and preventing hemorrhage have been extensively studied in the last decades. Knowing the mechanisms behind becomes very important particularly in the case of blood vessel diseases. Real-time and… read more here.
Keywords: coagulation; hyperspectral imaging; fluorescence hyperspectral; imaging fhsi ... See more keywords
Development of a User-Friendly App for Testing Blood Coagulation Status in Schizophrenia Patients.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-52479-5_34
Abstract: Blood coagulation time is an important factor to consider for postoperative and cardiac disorder patients who have been prescribed anticoagulant coagulant medications. The coagulation process is also known to be perturbed in some individuals with… read more here.
Keywords: development user; coagulation; user friendly; friendly app ... See more keywords
Importance of Initial Concentration of Factor VIII in a Mechanistic Model of In Vitro Coagulation
Sign Up to like & getrecommendations! Published in 2018 at "Acta Biotheoretica"
DOI: 10.1007/s10441-018-9329-8
Abstract: This computational study generates a hypothesis for the coagulation protein whose initial concentration greatly influences the course of coagulation. Many clinical malignancies of blood coagulation arise due to abnormal initial concentrations of coagulation factors. Sensitivity… read more here.
Keywords: coagulation; mechanistic model; model; initial concentration ... See more keywords
Inhibition of caspase-1-mediated inflammasome activation reduced blood coagulation in cerebrospinal fluid after subarachnoid haemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2022.103843
Abstract: Summary Background Neuroinflammation and blood coagulation responses in cerebrospinal fluid (CSF) contribute to the poor outcome associated with subarachnoid haemorrhage (SAH). We explored the role of caspase-1-mediated inflammasome activation on extrinsic blood coagulation in CSF… read more here.
Keywords: sah; inhibition caspase; caspase; blood coagulation ... See more keywords
Coagulopathy in patients with acute pulmonary embolism: a pilot study of whole blood coagulation and markers of endothelial damage
Sign Up to like & getrecommendations! Published in 2017 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2016.1239130
Abstract: Abstract Whole blood coagulation and markers of endothelial damage were studied in patients with acute pulmonary embolism (PE), and evaluated in relation to PE severity. Twenty-five patients were enrolled prospectively each having viscoelastical analysis of… read more here.
Keywords: patients acute; blood; endothelial damage; blood coagulation ... See more keywords
Effects of bisphenol A and S on blood coagulation: in vivo, in vitro and in silico approaches in toxicodynamic
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2020.1836102
Abstract: Abstract Bisphenol A (BPA) is a well-known endocrine disruptor with several effects on mammalian systems and has been linked to diseases, such as cancer. Bisphenol S (BPS) emerged as a likely alternative to BPA in… read more here.
Keywords: coagulation; bpa; time; bps ... See more keywords
Contemporary medicinal-chemistry strategies for discovery of blood coagulation factor Xa inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2019.1626821
Abstract: ABSTRACT Introduction: Thrombosis is a common causal pathology for stroke, acute coronary syndrome and venous thromboembolism disorders, which are the leading cause of death worldwide. Anticoagulants have exhibited a crucial role in the prevention and… read more here.
Keywords: fxa inhibitors; medicinal chemistry; chemistry; strategies discovery ... See more keywords
The use of blood coagulation products requires a thorough re‐evaluation
Sign Up to like & getrecommendations! Published in 2017 at "Acta Anaesthesiologica Scandinavica"
DOI: 10.1111/aas.12924
Abstract: The study by Vibede et al. raises a number of important points regarding the use of blood products and the management of coagulation disturbances that require further emphasis. As previously demonstrated by Holland and Brooks,… read more here.
Keywords: coagulation; ffp; use; use blood ... See more keywords
Establishment of gene‐edited pigs expressing human blood‐coagulation factor VII and albumin for bioartificial liver use
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.14666
Abstract: Bioartificial livers (BALs) are considered as a solution to bridge patients with acute liver failure to liver transplantation or to assist in spontaneous recovery for patients with end‐stage liver disease. Pig is the best donor… read more here.
Keywords: factor vii; pigs expressing; vii albumin; liver ... See more keywords
A new WHO reference reagent for activated blood coagulation factor X (FXa), human (15/102)
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DOI: 10.1111/jth.14623
Abstract: The existing standard for the measurement of activated blood coagulation factor X (FXa) is a non-WHO Reference Material (75/595) available from the National Institute for Biological Standards and Control (NIBSC). This bovine FXa reference material… read more here.
Keywords: reference; coagulation factor; factor fxa; blood coagulation ... See more keywords
Structural insights into blood coagulation factor VIII: Procoagulant complexes, membrane binding, and antibody inhibition
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.15793
Abstract: Advances in structural studies of blood coagulation factor VIII (FVIII) have provided unique insight into FVIII biochemistry. Atomic detail models of the B domain‐deleted FVIII structure alone and in complex with its circulatory partner, von… read more here.
Keywords: blood coagulation; factor; coagulation factor; factor viii ... See more keywords