Novel MRGPRX2 antagonists inhibit IgE‐independent activation of human umbilical cord blood‐derived mast cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.2ab1018-405r
Abstract: Human MCs are primary effectors implicated in immune surveillance and defense by secreting histamine and various inflammatory mediators, a mechanism termed as degranulation. MCs can be activated by two pathways: IgE‐dependent classical pathway and the… read more here.
Keywords: novel mrgprx2; independent activation; ige independent; blood derived ... See more keywords
Proteome Dynamics in Biobanked Horse Peripheral Blood Derived Lymphocytes (PBL) with Induced Autoimmune Uveitis
Sign Up to like & getrecommendations! Published in 2017 at "PROTEOMICS"
DOI: 10.1002/pmic.201700013
Abstract: Equine recurrent uveitis is the only spontaneous model for recurrent autoimmune uveitis in humans, where T cells target retinal proteins. Differences between normal and autoaggressive lymphocytes were identified in this study by analyzing peripheral blood… read more here.
Keywords: lymphocytes pbl; peripheral blood; autoimmune uveitis; derived lymphocytes ... See more keywords
Promising effects of exosomes isolated from menstrual blood‐derived mesenchymal stem cell on wound‐healing process in diabetic mouse model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2799
Abstract: Wound healing is a complicated process that contains a number of overlapping and consecutive phases, disruption in each of which can cause chronic nonhealing wounds. In the current study, we investigated the effects of exosomes… read more here.
Keywords: medicine; wound healing; menstrual blood; process ... See more keywords
Evaluation of different biological matrices to assess the vitamin D status in newborns using LC-MS/MS
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106368
Abstract: Abstract The main aim of this study was to show the usefulness of DBS samples in the assessment of a newborn's vitamin D body supply. Currently, maternal serum or umbilical cord blood-derived serum determinations are… read more here.
Keywords: cord blood; derived serum; dbs; blood derived ... See more keywords
Immunomodulatory Blood-Derived Hybrid Hydrogels as Multichannel Microenvironment Modulators for Augmented Bone Regeneration.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c16774
Abstract: Autologous blood-derived protein hydrogels have shown great promise in the field of personalized regenerative medicine. However, the inhospitable regenerative microenvironments, especially the unfavorable immune microenvironment, are closely associated with their limited tissue-healing outcomes. Herein, novel… read more here.
Keywords: immunomodulatory blood; microenvironment; hybrid hydrogels; blood derived ... See more keywords
Searching for the best blood-derived eye drops
Sign Up to like & getrecommendations! Published in 2018 at "Eye"
DOI: 10.1038/eye.2017.182
Abstract: 1 Talany G, Guo M, Etminan M. Risk of intraocular hemorrhage with new oral anticoagulants. Eye 2016; 174: 3158–3163. 2 Grzybowski A, Ascaso FJ, Kupidura-Majewski K, Packer M. Continuation of anticoagulant and antiplatelet therapy during… read more here.
Keywords: derived eye; eye drops; searching best; blood derived ... See more keywords
Homeostatic cytokines tune naivety and stemness of cord blood-derived transgenic T cells.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer gene therapy"
DOI: 10.1038/s41417-021-00395-5
Abstract: Engineered T-cell therapies have proven to be successful in cancer and their clinical effectiveness is directly correlated with the infused T-cell differentiation profile. Indeed, stem cell memory and central memory T cells proliferate and persist… read more here.
Keywords: transgenic cells; derived transgenic; cord blood; naivety stemness ... See more keywords
Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13058-z
Abstract: Despite the consistent rise of non-alcoholic steatohepatitis (NASH) worldwide, the mechanisms that govern the inflammatory aspect of this disease remain unknown. Previous research showed an association between hepatic inflammation and lysosomal lipid accumulation in blood-derived… read more here.
Keywords: hepatic inflammation; derived hepatic; inflammation; lysosomal lipids ... See more keywords
Efficient antisense inhibition reveals microRNA-155 to restrain a late-myeloid inflammatory programme in primary human phagocytes
Sign Up to like & getrecommendations! Published in 2021 at "RNA Biology"
DOI: 10.1080/15476286.2021.1885209
Abstract: ABSTRACT A persisting obstacle in human immunology is that blood-derived leukocytes are notoriously difficult to manipulate at the RNA level. Therefore, our knowledge about immune-regulatory RNA-networks is largely based on tumour cell-line and rodent knockout… read more here.
Keywords: microrna 155; biology; blood derived; primary human ... See more keywords
Transplantation of umbilical cord blood-derived mesenchymal stem cells as therapy for adriamycin induced-cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2061145
Abstract: ABSTRACT Umbilical cord blood-derived mesenchymal stem cells (UCBMSCs) have been reported to possess cardioprotective effects in diseases. However, its effects on cardiomyopathy remain unclear. This study aimed to the therapeutic effects of UCBMSC transplantation on… read more here.
Keywords: derived mesenchymal; umbilical cord; cord blood; blood derived ... See more keywords
Identification and verification of differentially expressed key genes in peripheral blood-derived T cells between chronic immune thrombocytopenia patients and healthy controls
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2080422
Abstract: ABSTRACT Immune thrombocytopenia (ITP), characterized by decreased platelet counts, is a complex immune-mediated disorder with unelucidated pathogenesis. Accumulating evidence shows that T cell-mediated platelet destruction is one crucial process during the progression of ITP. Here,… read more here.
Keywords: immune thrombocytopenia; genes peripheral; itp; blood derived ... See more keywords