Fire-shaped cylindrical glass micronozzles to measure cell deformability
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Micromechanics and Microengineering"
DOI: 10.1088/1361-6439/ab3183
Abstract: Most of the blood cells exhibit a natural deformation capability. Specifically, Red Blood Cells (RBCs) are characterized by their great ability to deform and squeeze through microcapillary vessels, even with strict restrictions, recovering their shape… read more here.
Keywords: blood; cell deformability; blood diseases; glass ... See more keywords
Nanopore Sequencing in Blood Diseases: A Wide Range of Opportunities
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2020.00076
Abstract: The molecular pathogenesis of hematological diseases is often driven by genetic and epigenetic alterations. Next-generation sequencing has considerably increased our genomic knowledge of these disorders becoming ever more widespread in clinical practice. In 2012 Oxford… read more here.
Keywords: sequencing blood; range opportunities; diseases wide; nanopore sequencing ... See more keywords
Inflammasomes—New Contributors to Blood Diseases
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158129
Abstract: Inflammasomes are intracellular multimeric complexes that cleave the precursors of the IL-1 family of cytokines and various proteins, found predominantly in cells of hematopoietic origin. They consist of pattern-recognition receptors, adaptor domains, and the enzymatic… read more here.
Keywords: inflammasomes new; contributors blood; inflammasome; new contributors ... See more keywords
Aptamers: Potential Diagnostic and Therapeutic Agents for Blood Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27020383
Abstract: Aptamers are RNA/DNA oligonucleotide molecules that specifically bind to a targeted complementary molecule. As potential recognition elements with promising diagnostic and therapeutic applications, aptamers, such as monoclonal antibodies, could provide many treatment and diagnostic options… read more here.
Keywords: aptamers potential; diseases aptamers; diagnostic therapeutic; potential diagnostic ... See more keywords