Novel associations between blood DNA methylation and body mass index in middle-aged and older adults
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DOI: 10.1038/ijo.2017.269
Abstract: Background/Objectives:There is increasing evidence of a relationship between blood DNA methylation and body mass index (BMI). We aimed to assess associations of BMI with individual methylation measures (CpGs) through a cross-sectional genome-wide DNA methylation association… read more here.
Keywords: methylation body; blood dna; methylation; dna methylation ... See more keywords
DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome
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DOI: 10.1111/acel.13555
Abstract: Hutchinson–Gilford Progeria Syndrome (HGPS) is an extremely rare genetic disorder caused by mutations in the LMNA gene and characterized by premature and accelerated aging beginning in childhood. In this study, we performed the first genome‐wide… read more here.
Keywords: methylation; dna; gilford progeria; hutchinson gilford ... See more keywords
Arsenic Exposure, Blood DNA Methylation, and Cardiovascular Disease
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DOI: 10.1161/circresaha.122.320991
Abstract: Background: Epigenetic dysregulation has been proposed as a key mechanism for arsenic-related cardiovascular disease (CVD). We evaluated differentially methylated positions (DMPs) as potential mediators on the association between arsenic and CVD. Methods: Blood DNA methylation… read more here.
Keywords: dna; cardiovascular disease; dna methylation; cvd ... See more keywords
Maternal eating disorders affect offspring cord blood DNA methylation: a prospective study
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DOI: 10.1186/s13148-017-0418-3
Abstract: BackgroundEating disorders (ED) are chronic psychiatric disorders, common amongst women of reproductive age. ED in pregnancy are associated with poor nutrition and abnormal intrauterine growth. Increasing evidence also shows offspring of women with ED have… read more here.
Keywords: methylation; cord blood; offspring women; blood dna ... See more keywords
Maternal Dietary Glycemic Index and Glycemic Load in Pregnancy and Offspring Cord Blood DNA Methylation.
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DOI: 10.2337/dc21-2662
Abstract: OBJECTIVE Suboptimal nutrition in pregnancy is associated with worse offspring cardiometabolic health. DNA methylation may be an underlying mechanism. We meta-analyzed epigenome-wide association studies (EWAS) of maternal dietary glycemic index and load with cord blood… read more here.
Keywords: glycemic index; dna methylation; dna; blood dna ... See more keywords