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Published in 2019 at "European journal of internal medicine"
DOI: 10.1016/j.ejim.2019.07.005
Abstract: Disease phenotyping is a key step towards an increasingly personalized approach to chronic obstructive pulmonary disease (COPD), leading to a more precise assessment, treatment and definition of disease outcomes. The search for biomarkers able to…
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Keywords:
chronic obstructive;
response;
obstructive pulmonary;
disease ... See more keywords
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Published in 2018 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2018.06.025
Abstract: BACKGROUND Eosinophilic asthma is characterized by persistently elevated blood eosinophils, adult-onset asthma and corticosteroid resistance. For stratified medicine purposes one single measurement of blood eosinophils or exhaled nitric oxide (FeNO) is commonly used. The aim…
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Keywords:
exhaled nitric;
blood eosinophils;
cut;
blood ... See more keywords
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Published in 2018 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2018.07.011
Abstract: BACKGROUND Low-grade systemic inflammation, mainly assessed by C-reactive protein (CRP), has been associated with impaired lung function. Few studies have studied if CRP, blood eosinophils, and blood neutrophils offer additive information in relation to lung…
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Keywords:
blood eosinophils;
blood;
eosinophils blood;
lung function ... See more keywords
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Published in 2022 at "Annals of Medicine"
DOI: 10.1080/07853890.2022.2134584
Abstract: Abstract Purpose The relationship between childhood blood eosinophils and subtypes of allergic diseases remains understudied. This study aimed to examine the associations between childhood blood eosinophils and subtypes of asthma, rhinitis and dermatitis, as well…
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Keywords:
asthma rhinitis;
childhood blood;
rhinitis;
allergic asthma ... See more keywords
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Published in 2021 at "COPD: Journal of Chronic Obstructive Pulmonary Disease"
DOI: 10.1080/15412555.2021.1985989
Abstract: Abstract Blood eosinophils have been proposed as a surrogate biomarker of airway eosinophilia that can be used for treatment decisions in patients with COPD, mainly for the identification of candidates for the initiation or withdrawal…
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Keywords:
copd attempt;
eosinophils management;
blood eosinophils;
copd ... See more keywords
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Published in 2018 at "Respirology"
DOI: 10.1111/resp.13200
Abstract: After a lifetime of being seen but not noticed, the blood eosinophil count has now taken centre stage as the most clinically accessible biomarker to aid in the management of asthma and COPD. Phenotyping has…
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Keywords:
blood eosinophil;
eosinophil counts;
blood eosinophils;
blood ... See more keywords
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Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-058215
Abstract: Introduction The reduction of the risk of asthma attacks is a major goal of guidelines. The fact that type-2 inflammatory biomarkers identify a higher risk, anti-inflammatory responsive phenotype is potentially relevant to this goal. We…
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Keywords:
asthma attacks;
risk;
blood eosinophils;
control arm ... See more keywords
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Published in 2018 at "Thorax"
DOI: 10.1136/thorax-2018-212555.281
Abstract: Introduction and objectives Blood eosinophils are a potentially useful biomarker to guide inhaled corticosteroid (ICS) treatment in COPD. We aimed to investigate whether blood eosinophil count predicts the effect of maintenance treatment with ICS versus…
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Keywords:
primary care;
maintenance;
treatment;
blood eosinophils ... See more keywords
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Published in 2017 at "Thorax"
DOI: 10.1136/thoraxjnl-2017-210983.155
Abstract: Introduction Severe Asthma, characterised by persistent symptoms despite maximal medical therapy, represents 5% of asthma cases. Bronchial Thermoplasty (BT) is a novel therapy where radiofrequency thermal energy is applied to airways distal to the main-stem…
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Keywords:
year;
severe asthma;
blood eosinophils;
peripheral blood ... See more keywords
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Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.oa492
Abstract: Background: It is believed that high blood eosinophils are important indicators of poor prognosis and increased exacerbations in COPD. However, variability and long term role of these cells in COPD is not known. Aim: Long…
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Keywords:
clinical outcomes;
long term;
variability;
blood eosinophils ... See more keywords
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Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.pa4758
Abstract: Background: One of the main severe asthma phenotype is the “severe eosinophilic” or “eosinophilic refractory” asthma, for which novel biologic agents are emerging as therapeutical options. In this context, blood eosinophils count are one of…
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Keywords:
point care;
blood eosinophils;
blood;
severe asthma ... See more keywords