Notch activation is required for downregulation of HoxA3-dependent endothelial cell phenotype during blood formation
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DOI: 10.1371/journal.pone.0186818
Abstract: Hemogenic endothelium (HE) undergoes endothelial-to-hematopoietic transition (EHT) to generate blood, a process that requires progressive down-regulation of endothelial genes and induction of hematopoietic ones. Previously, we have shown that the transcription factor HoxA3 prevents blood… read more here.
Keywords: notch activation; blood; hoxa3; blood formation ... See more keywords