Whole-Blood Gene Expression Profile After Hypoxic-Ischemic Encephalopathy
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.54433
Abstract: This case-control study compares the genome expression at birth and associated outcome in neonates with hypoxic-ischemic encephalopathy in a high-income country (Italy) and their counterparts in low- to middle-income countries (India, Sri Lanka, and Bangladesh). read more here.
Keywords: whole blood; gene expression; hypoxic ischemic; blood gene ... See more keywords
The contribution of genetic determinants of blood gene expression and splicing to molecular phenotypes and health outcomes
Sign Up to like & getrecommendations! Published in 2025 at "Nature Genetics"
DOI: 10.1038/s41588-025-02096-3
Abstract: The biological mechanisms through which most nonprotein-coding genetic variants affect disease risk are unknown. To investigate gene-regulatory mechanisms, we mapped blood gene expression and splicing quantitative trait loci (QTLs) through bulk RNA sequencing in 4,732… read more here.
Keywords: gene expression; etiology; blood gene; expression ... See more keywords
Peripheral blood gene expression reveals an inflammatory transcriptomic signature in Friedreich’s ataxia patients
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DOI: 10.1093/hmg/ddy198
Abstract: Abstract Transcriptional changes in Friedreich’s ataxia (FRDA), a rare and debilitating recessive Mendelian neurodegenerative disorder, have been studied in affected but inaccessible tissues—such as dorsal root ganglia, sensory neurons and cerebellum—in animal models or small… read more here.
Keywords: friedreich ataxia; blood gene; peripheral blood; expression ... See more keywords
Physical activity and blood gene expression profiles: the Norwegian Women and Cancer (NOWAC) Post-genome cohort
Sign Up to like & getrecommendations! Published in 2020 at "BMC Research Notes"
DOI: 10.1186/s13104-020-05121-2
Abstract: Objectives The influence of physical activity (PA) on the immune system has emerged as a new field of research. Regular PA may promote an anti-inflammatory state in the body, thus contributing to the down-regulation of… read more here.
Keywords: norwegian women; expression profiles; blood gene; gene expression ... See more keywords