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Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.711
Abstract: Teriflunomide, a disease‐modifying treatment approved for multiple sclerosis (MS), inhibits reversibly dihydroorotate dehydrogenase, an enzyme involved in de novo pyrimidine biosynthesis and down‐regulates proliferation of activated lymphocytes. We aimed to study the impact of this…
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Keywords:
blood immune;
tolerogenic bias;
induces tolerogenic;
immune cells ... See more keywords
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1
Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0264631
Abstract: Clinical adoption of immune checkpoint inhibitors in cancer management has highlighted the interconnection between carcinogenesis and the immune system. Immune cells are integral to the tumour microenvironment and can influence the outcome of therapies. Better…
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Keywords:
blood immune;
immune signatures;
tumour;
blood ... See more keywords
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1
Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.967921
Abstract: Current non-invasive tumor biomarkers failed to accurately identify patients with colorectal cancer (CRC), delaying CRC diagnosis and thus leading to poor prognosis. Dysregulation of 5-Methylcytosine (m5C) RNA has gradually been reported in various cancers, but…
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Keywords:
blood immune;
diagnosis;
immune cells;
blood ... See more keywords
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1
Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13020190
Abstract: In this exploratory prospective observational study on 40 small cell lung cancer (SCLC) patients treated with a combination of chemotherapy and immune checkpoint inhibitors, blood immune cells were characterized by multi-color flow cytometry at the…
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Keywords:
lung cancer;
cell;
blood immune;
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0
Published in 2020 at "Immune Network"
DOI: 10.4110/in.2020.20.e8
Abstract: Immune checkpoint blockade targeting PD-1 and PD-L1 has resulted in unprecedented clinical benefit for cancer patients. Anti-PD-1/PD-L1 therapy has become the standard treatment for diverse cancer types as monotherapy or in combination with other anti-cancer…
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Keywords:
therapy;
peripheral blood;
anti therapy;
blood immune ... See more keywords