Epigenetic Response to Mindfulness in Peripheral Blood Leukocytes Involves Genes Linked to Common Human Diseases
Sign Up to like & getrecommendations! Published in 2018 at "Mindfulness"
DOI: 10.1007/s12671-017-0851-6
Abstract: The benefits of mindfulness on human health are well-documented, but the mechanisms underlying these effects are not well-understood. Our aim was to identify molecular alterations related to mindfulness by profiling the epigenetic response in long-term… read more here.
Keywords: mindfulness; response; blood leukocytes; peripheral blood ... See more keywords
hTERT promoter methylation status in peripheral blood leukocytes as a molecular marker of head and neck cancer progression
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Genetics"
DOI: 10.1007/s13353-018-0458-1
Abstract: Cancer cells, including head and neck cancer cell carcinoma (HNSCC), are characterized by an increased telomerase activity. This enzymatic complex is active in approximately 80–90% of all malignancies, and is regulated by various factors, including… read more here.
Keywords: methylation; blood leukocytes; methylation status; promoter ... See more keywords
Expression profiles of candidate microRNAs in the peripheral blood leukocytes of patients with early- and late-onset preeclampsia versus normal pregnancies.
Sign Up to like & getrecommendations! Published in 2019 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2019.11.003
Abstract: OBJECTIVES Maternal leucocytes play an important role in the pathogenesis of preeclampsia (PE). Circulating microRNAs (miRNAs) are small, noncoding RNA molecules. The purpose of this study was to investigate miR-518b, miR-155-5p, and miR-21-3p in the… read more here.
Keywords: late onset; blood leukocytes; mir 518b; peripheral blood ... See more keywords
Association of accelerated dynamics of telomere sequence loss in peripheral blood leukocytes with incident knee osteoarthritis in Osteoarthritis Initiative cohort
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DOI: 10.1038/s41598-021-95326-7
Abstract: Osteoarthritis (OA) is a chronic degenerative joint disease, being the main cause of laboral inability. Decreased telomere size in peripheral blood leukocytes (PBL) has been correlated with age-related pathologies, like knee OA. In a dynamic… read more here.
Keywords: blood leukocytes; telomere loss; osteoarthritis; peripheral blood ... See more keywords
Segmentation of White Blood Cells Based on CBAM-DC-UNet
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DOI: 10.1109/access.2022.3233078
Abstract: Monitoring the morphology of blood leukocytes, plays an important role in medical research, especially in the treatment of diseases such as immunodeficiency. Traditional manual detection methods are susceptible to numerous interference factors. Therefore, blood cells… read more here.
Keywords: blood leukocytes; blood cells; segmentation; blood ... See more keywords
Dose Dependence of Hypermethylation of Gene Promoters in Blood Leukocytes in Humans Occupationally Exposed to External γ-Radiation
Sign Up to like & getrecommendations! Published in 2019 at "Biology Bulletin"
DOI: 10.1134/s1062359019110062
Abstract: Abstract—A study of promoter hypermethylation of cell cycle (RASSF1A, p16/INK4A, p14/ARF, p53, АТМ), xenobiotic detoxification (GSTP1), antioxidant defense (SOD3), and estrogen receptor (ESR1) genes in blood leukocytes of 88 nuclear industry workers from the Mayak… read more here.
Keywords: hypermethylation; gene promoters; radiation; external radiation ... See more keywords
Correlation between global methylation level of peripheral blood leukocytes and serum C reactive protein level modified by MTHFR polymorphism: a cross-sectional study
Sign Up to like & getrecommendations! Published in 2018 at "BMC Cancer"
DOI: 10.1186/s12885-018-4089-z
Abstract: BackgroundChronic inflammatory conditions are associated with higher tumor incidence through epigenetic and genetic alterations. Here, we focused on an association between an inflammation marker, C-reactive-protein (CRP), and global DNA methylation levels of peripheral blood leukocytes.MethodsThe… read more here.
Keywords: methylation; blood leukocytes; methylation level; level ... See more keywords
Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patients
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DOI: 10.1371/journal.pone.0271637
Abstract: Objective Patients admitted to the Intensive Care Unit (ICU) oftentimes show immunological signs of immune suppression. Consequently, immune stimulatory agents have been proposed as an adjunctive therapy approach in the ICU. The objective of this… read more here.
Keywords: immune suppression; blood leukocytes; procoagulant responses; suppression associated ... See more keywords
The Variants at APOA1 and APOA4 Contribute to the Susceptibility of Schizophrenia With Inhibiting mRNA Expression in Peripheral Blood Leukocytes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.785445
Abstract: Objective: Abnormal lipid metabolism has a close link to the pathophysiology of schizophrenia (SZ). This study mainly aimed to evaluate the association of variants at apolipoprotein A1 (APOA1) and APOA4 with SZ in a Chinese… read more here.
Keywords: peripheral blood; apoa1 apoa4; expression; mrna expression ... See more keywords
Transient Receptor Potential Ankyrin 1 Channel Expression on Peripheral Blood Leukocytes from Rheumatoid Arthritic Patients and Correlation with Pain and Disability
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00053
Abstract: Patients with rheumatoid arthritis (RA) suffer from pain and joint disability. The transient receptor potential ankyrin 1 (TRPA1) channel expressed on sensory neurones and non-neuronal cells mediates pain transduction and inflammation and it has been… read more here.
Keywords: peripheral blood; expression; pain disability; blood leukocytes ... See more keywords