Enzymatically Crosslinked Collagen as a Versatile Matrix for In Vitro and In Vivo Co‐Engineering of Blood and Lymphatic Vasculature
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DOI: 10.1002/adma.202209476
Abstract: Adequate vascularization is required for the successful translation of many in vitro engineered tissues. This study presents a novel collagen derivative that harbors multiple recognition peptides for orthogonal enzymatic crosslinking based on sortase A (SrtA)… read more here.
Keywords: vitro vivo; crosslinking; collagen; blood ... See more keywords
Blood‐Lymphatic Integrated System with Heterogeneous Melanoma Spheroids via In‐Bath Three‐Dimensional Bioprinting for Modelling of Combinational Targeted Therapy
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DOI: 10.1002/advs.202202093
Abstract: Although metastatic melanoma can be managed with chemotherapy, its heterogeneity and resistance to therapy remain poorly understood. In addition to the spread of melanoma in the bloodstream, melanoma‐stroma interaction and the lymphatic system play active… read more here.
Keywords: system; lymphatic integrated; melanoma spheroids; melanoma ... See more keywords
Opposing Roles of Vascular Endothelial Growth Factor C in Metastatic Dissemination and Resistance to Radio/Chemotherapy: Discussion of Mechanisms and Therapeutic Strategies.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2217-9_1
Abstract: Many cancers can be cured by combining surgery with healthy margins, radiation therapy and chemotherapies. However, when the pathology becomes metastatic, cancers can be incurable. The best situation involves "chronicization" of the pathology even for… read more here.
Keywords: pathology; cancer cells; blood lymphatic; cancer ... See more keywords
Multilayer microfluidic platform for the study of luminal, transmural, and interstitial flow
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DOI: 10.1088/1758-5090/ac48e5
Abstract: Efficient delivery of oxygen and nutrients to tissues requires an intricate balance of blood, lymphatic, and interstitial fluid pressures (IFPs), and gradients in fluid pressure drive the flow of blood, lymph, and interstitial fluid through… read more here.
Keywords: flow; microfluidic platform; fluid; blood ... See more keywords
UV light crosslinking regresses mature corneal blood and lymphatic vessels and promotes subsequent high‐risk corneal transplant survival
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DOI: 10.1111/ajt.14874
Abstract: Immunologic graft rejection is the main complication after corneal transplant into pathologically prevascularized so‐called high‐risk eyes. The aim of this study was to evaluate whether ultraviolet (UV) light crosslinking can regress pathologic corneal blood and… read more here.
Keywords: lymphatic vessels; high risk; corneal; blood lymphatic ... See more keywords