Association between Human Blood Metabolome and the Risk of Alzheimer's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26464
Abstract: Alzheimer's disease (AD) is the most common degenerative neurological disorder with limited therapeutic options. Therefore, it is particularly important to explore the potential biomarkers implicated in the occurrence and progression of AD prior to clinical… read more here.
Keywords: metabolome risk; disease; alzheimer disease; association human ... See more keywords
Association Between Human Blood Metabolome and the Risk of Psychiatric Disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sbac130
Abstract: BACKGROUND AND HYPOTHESIS To identify promising drug targets for psychiatric disorders, we applied Mendelian randomization (MR) design to systematically screen blood metabolome for potential mediators of psychiatric disorders and further predict target-mediated side effects. STUDY… read more here.
Keywords: psychiatric disorders; side effects; blood; disorder ... See more keywords
Association of the characteristics of the blood metabolome and gut microbiome with the outcome of methotrexate therapy in psoriasis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.937539
Abstract: Metabolic status and gut microecology are implicated in psoriasis. Methotrexate (MTX) is usually the first-line treatment for this disease. However, the relationship between MTX and host metabolic status and the gut microbiota is unclear. This… read more here.
Keywords: metabolome gut; mtx; gut microbiome; psoriasis ... See more keywords
High Intensity Concentric-Eccentric Exercise Under Hypoxia Changes the Blood Metabolome of Trained Athletes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.904618
Abstract: The aim of this study was to determine alterations of the metabolome in blood plasma in response to concentric-eccentric leg exercise performed at a simulated altitude of 3,500 m. To do so, we recruited 11… read more here.
Keywords: concentric eccentric; eccentric exercise; intensity concentric; high intensity ... See more keywords
The Diurnal Blood Metabolome and Effects of Vitamin D Supplementation: A Randomised Crossover Trial in Postmenopausal Women
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179748
Abstract: A way to maintain an adequate vitamin D status is through supplementation. Demonstration of blood-metabolome rhythmicity of vitamin D3 post-dosing effects is lacking in the pharmaco-metabonomics area. Thus, the overall aim of this study was… read more here.
Keywords: blood metabolome; supplementation; postmenopausal women; vitamin supplementation ... See more keywords