Lipid Alteration Signature in the Blood Plasma of Individuals With Schizophrenia, Depression, and Bipolar Disorder.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2022.4350
Abstract: Importance No clinically applicable diagnostic test exists for severe mental disorders. Lipids harbor potential as disease markers. Objective To define a reproducible profile of lipid alterations in the blood plasma of patients with schizophrenia (SCZ)… read more here.
Keywords: bpd mdd; blood plasma; bipolar disorder; plasma ... See more keywords
Protein Corona: Prevention of Dominant IgG Adsorption on Nanocarriers in IgG‐Enriched Blood Plasma by Clusterin Precoating (Adv. Sci. 10/2019)
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Science"
DOI: 10.1002/advs.201970062
Abstract: The development of nanocarriers for drug delivery is challenged by individual blood composition fluctuations. In article number 1802199, Svenja Morsbach and co‐workers report the accumulation of immunoglobulins in the protein corona of nanocarriers in IgG‐enriched… read more here.
Keywords: protein corona; blood; enriched blood; nanocarriers igg ... See more keywords
Low-volume LC-MS/MS method for the pharmacokinetic investigation of carvedilol, enalapril and their metabolites in whole blood and plasma: application to a paediatric clinical trial.
Sign Up to like & getrecommendations! Published in 2020 at "Drug testing and analysis"
DOI: 10.1002/dta.2949
Abstract: Evidence-based pharmacotherapy with carvedilol and enalapril in children suffering from heart failure is insufficient owing to limited pharmacokinetic data.1 While a few datasets regarding enalapril, its metabolite enalaprilat and carvedilol in children have been published,… read more here.
Keywords: carvedilol; blood; whole blood; blood plasma ... See more keywords
Capillary electrophoresis coupled with chloroform‐acetonitrile extraction for rapid and highly selective determination of cysteine and homocysteine levels in human blood plasma and urine
Sign Up to like & getrecommendations! Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700133
Abstract: A rapid and selective method has been developed for highly sensitive determination of total cysteine and homocysteine levels in human blood plasma and urine by capillary electrophoresis (CE) coupled with liquid–liquid extraction. Analytes were first… read more here.
Keywords: extraction; plasma urine; homocysteine; human blood ... See more keywords
Metabolomic profiling of blood plasma in patients with primary brain tumours: Basal plasma metabolites correlated with tumour grade and plasma biomarker analysis predicts feasibility of the successful statistical discrimination from healthy subjects – a preliminary study
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2149
Abstract: The brain tumours represent a complex tissue that has its own characteristic metabolic features and is interfaced with the whole organism. We investigated changes in basal blood plasma metabolites in the presence of primary brain… read more here.
Keywords: primary brain; plasma metabolites; plasma; blood plasma ... See more keywords
Platelet removal from human blood plasma improves detection of extracellular vesicle‐associated miRNA
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12302
Abstract: Abstract Human blood plasma prepared by centrifugation contains not only extracellular vesicles (EVs) but also platelets and erythrocyte ghosts (ery‐ghosts). Here we studied whether analysis of miRNA associated with plasma EVs (EV‐miRNA) is affected by… read more here.
Keywords: blood plasma; ery ghosts; human blood; mirna ... See more keywords
Comparison of proteomic approaches used for the detection of potential biomarkers of Alzheimer's disease in blood plasma.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202100468
Abstract: At present, Alzheimer´s disease is detected mainly using psychological tests, which, can only confirm the disease in its more advanced phases. Therefore, bioanalytical possibilities for detecting this disease earlier are being investigated. To date, the… read more here.
Keywords: potential biomarkers; alzheimer disease; blood plasma; disease ... See more keywords
Abnormalities in metabolic pathways in celiac disease investigated by the metabolic profiling of small intestinal mucosa, blood plasma and urine by NMR spectroscopy
Sign Up to like & getrecommendations! Published in 2020 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4305
Abstract: Celiac disease (CeD) is an autoimmune enteropathy caused by gluten intake in genetically predisposed individuals. We investigated the metabolism of CeD by metabolic profiling of intestinal mucosa, blood plasma and urine using NMR spectroscopy and… read more here.
Keywords: plasma urine; intestinal mucosa; spectroscopy; mucosa blood ... See more keywords
Lipidomics of Human Blood Plasma by High-Resolution Shotgun Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7057-5_16
Abstract: Clinical lipidomics is an emerging biomarker discovery approach that compares lipid profiles under pathologically and physiologically normal conditions. Here we describe a method for the absolute (molar) quantification of more than 200 molecules from 14… read more here.
Keywords: high resolution; mass spectrometry; shotgun mass; human blood ... See more keywords
A sensitive HPLC-MS/MS method for the detection, resolution and quantitation of cathinone enantiomers in horse blood plasma and urine
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-021-03182-1
Abstract: Resolution of cathinone enantiomers in equine anti-doping analysis is becoming more important to distinguish the inadvertent ingestion of plant-based products from those of deliberate administration of designer synthetic analogs. With this in mind, a rapid… read more here.
Keywords: detection; plasma urine; cathinone enantiomers; cathinone ... See more keywords
Laser-induced changes of in vitro erythrocyte sedimentation rate
Sign Up to like & getrecommendations! Published in 2017 at "Lasers in Medical Science"
DOI: 10.1007/s10103-017-2340-5
Abstract: The study of the effects of low-level laser (LLL) radiation on blood is important for elucidating the mechanisms behind the interaction of LLL radiation and biologic tissues. Different therapy methods that involve blood irradiation have… read more here.
Keywords: plasma; laser; blood; irradiated blood ... See more keywords