Dried blood spot collection, sample quality, and fieldwork conditions: Structural validations for conversion into standard values
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Human Biology"
DOI: 10.1002/ajhb.23517
Abstract: SHARE, a pan‐European panel study in 27 European countries and Israel, has collected dried blood spot (DBS) samples from approximately 27 000 respondents in 13 countries. We aim to obtain factors to convert analyte values between… read more here.
Keywords: spot; fieldwork conditions; blood spot; dried blood ... See more keywords
Evaluation of fibronectin 1 in one dried blood spot and in urine after rhGH treatment.
Sign Up to like & getrecommendations! Published in 2017 at "Drug testing and analysis"
DOI: 10.1002/dta.2108
Abstract: Since the appearance of recombinant human growth hormone (rhGH) in the 1980s, its expansion and acquisition through the black market has increased, so the detection of its abuse continues to be a challenge. New biomarkers… read more here.
Keywords: one dried; spot urine; rhgh; blood spot ... See more keywords
Doping control analysis of trimetazidine in dried blood spot.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3414
Abstract: Dried blood spot (DBS) analysis has been an inherent part of sports drug testing through the technological advancements of the past decade. Trimetazidine, a non-threshold banned substance, is excreted into urine after a dose of… read more here.
Keywords: blood spot; trimetazidine; dried blood; analysis ... See more keywords
An improved functional assay in blood spot to diagnose Barth syndrome using the monolysocardiolipin/cardiolipin ratio.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of inherited metabolic disease"
DOI: 10.1002/jimd.12425
Abstract: Barth syndrome is an X-linked disorder characterized by cardiomyopathy, skeletal myopathy and neutropenia, caused by deleterious variants in TAFAZZIN. This gene encodes a phospholipid-lysophospholipid transacylase that is required for the remodeling of the mitochondrial phospholipid… read more here.
Keywords: barth syndrome; blood spot; cardiolipin;
Clinical validation of novel dried blood spot based collecting device using serum separation for measuring SARS‐CoV‐2 antibodies
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28765
Abstract: Accurate surveillance of coronavirus disease 2019 (COVID‐19) incidence includes large‐scale antibody testing of the population. Current testing methods require collection of venous blood samples by a healthcare worker, or dried blood spot (DBS) collection using… read more here.
Keywords: blood spot; cov antibodies; dried blood; blood ... See more keywords
Clinical validation study of dried blood spot for determining everolimus concentration in patients with cancer
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-017-2394-0
Abstract: PurposeEverolimus treatment is seriously hampered by its toxicity profile. As a relationship between everolimus exposure and effectiveness and toxicity has been established, early and ongoing concentration measurement can be key to individualize the dose and… read more here.
Keywords: cancer; concentration; blood spot; dried blood ... See more keywords
Analysis of tamoxifen and its metabolites in dried blood spot and volumetric absorptive microsampling: comparison and clinical application
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e07275
Abstract: This research was conducted to develop the Dried Blood Spot (DBS) and Volumetric Absorptive Microsampling (VAMS) method in the analysis of Tamoxifen (TAM) and its metabolites endoxifen (END), 4-hydroxytamoxifen (4-HT), and N-desmethyltamoxifen (NDT) using Ultra… read more here.
Keywords: absorptive microsampling; analysis; blood spot; volumetric absorptive ... See more keywords
Simultaneous determination of cardiovascular drugs in dried blood spot by liquid chromatography-tandem mass spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of food and drug analysis"
DOI: 10.1016/j.jfda.2019.06.001
Abstract: A dried blood spot (DBS) sampling method was exploited to extract cardiovascular drugs using a small volume of whole blood of human and rodent. Thereafter, an analytical method using liquid chromatography with tandem mass spectrometry… read more here.
Keywords: cardiovascular drugs; blood spot; blood; chromatography tandem ... See more keywords
Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2016.12.012
Abstract: &NA; Miltefosine is an oral agent against the neglected tropical disease leishmaniasis, which is mostly endemic in resource‐poor areas. Dried blood spot (DBS) sampling is an attractive alternative to plasma sampling for pharmacokinetic studies in… read more here.
Keywords: microsampling vams; absorptive microsampling; blood spot; dried blood ... See more keywords
Is the hematocrit still an issue in quantitative dried blood spot analysis?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.10.010
Abstract: &NA; Hematocrit‐related issues remain a major barrier for (regulatory) acceptance of the classical dried blood spot (DBS) analysis in the bioanalytical and clinical field. Lately, many attempts to cope with these issues have been made.… read more here.
Keywords: dried blood; hematocrit; analysis; blood spot ... See more keywords
Development of a fast LC‐MS/MS protocol for combined measurement of six LSDs on dried blood spot in a newborn screening program
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.12.002
Abstract: Graphical abstract Figure. No Caption available. HighlightsSix enzyme activities were dosed simultaneously on one DBS.A new chromatographic plumbing allowed product elution and cleaning up within 4.5 min avoiding column and valco valve stress.A faster analytical… read more here.
Keywords: protocol; blood spot; newborn screening; dried blood ... See more keywords