The Atlantic salmon whole blood transcriptome and how it relates to major locus maturation genotypes and other tissues.
Sign Up to like & getrecommendations! Published in 2021 at "Marine genomics"
DOI: 10.1016/j.margen.2020.100809
Abstract: The Atlantic salmon (Salmo salar) is important to many ecosystems and local economies and has therefore become the focus of a broad range of research questions that have benefited from the availability of high-quality genomic… read more here.
Keywords: blood transcriptome; blood; atlantic salmon; whole blood ... See more keywords
Blood transcriptome comparison between sexes and their function in 4-week Rhode Island red chickens
Sign Up to like & getrecommendations! Published in 2022 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2022.2146187
Abstract: ABSTRACT Sex is a major biological factor in the development and physiology of a sexual reproductive organism, and its role in the growing process is needed to be investigated in various species. We compare blood… read more here.
Keywords: development; island red; rhode island; red chickens ... See more keywords
Longitudinal Analyses of Blood Transcriptome During Conversion to Psychosis
Sign Up to like & getrecommendations! Published in 2019 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sby009
Abstract: The biological processes associated with the onset of schizophrenia remain largely unknown. Current hypotheses favor gene × environment interactions as supported by our recent report about DNA methylation changes during the onset of psychosis. Here,… read more here.
Keywords: longitudinal analyses; analyses blood; blood transcriptome; conversion ... See more keywords
Whole‐blood transcriptome analysis reveals distinct gene expression signatures in paediatric patients with sickle cell anaemia before and after exercise
Sign Up to like & getrecommendations! Published in 2024 at "British Journal of Haematology"
DOI: 10.1111/bjh.19533
Abstract: Sickle cell anaemia (SCA) patients display elevated levels of circulating pro‐inflammatory cytokines and endothelial activation markers compared to healthy peers. The impact of exercise on the pro‐inflammatory state in SCA remains unclear. This study aimed… read more here.
Keywords: blood transcriptome; exercise; whole blood; sca patients ... See more keywords
Predicting tissue-specific gene expression from whole blood transcriptome
Sign Up to like & getrecommendations! Published in 2021 at "Science Advances"
DOI: 10.1126/sciadv.abd6991
Abstract: Machine learning tool TEEBoT predicts an individual’s tissue-specific gene expression from his/her blood transcriptome. Complex diseases are mediated via transcriptional dysregulation in multiple tissues. Thus, knowing an individual’s tissue-specific gene expression can provide critical information… read more here.
Keywords: blood transcriptome; tissue specific; expression; tissue ... See more keywords
Whole blood transcriptome characterization of young female triathlon athletes following an endurance exercise: a pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Genomics"
DOI: 10.1152/physiolgenomics.00090.2022
Abstract: The vast majority of studies focusing on the effects of endurance exercise on hematological parameters and leukocyte gene expression were performed in adult men, so our aim was to investigate these changes in young females.… read more here.
Keywords: endurance exercise; exercise; whole blood; blood ... See more keywords
A clinically validated human capillary blood transcriptome test for global systems biology studies.
Sign Up to like & getrecommendations! Published in 2020 at "BioTechniques"
DOI: 10.2144/btn-2020-0088
Abstract: To prevent and treat chronic diseases, including cancer, a global application of systems biology is needed. We report here a whole blood transcriptome test that needs only 50 μl of capillary (fingerprick) blood. This test is… read more here.
Keywords: transcriptome test; blood transcriptome; biology; blood ... See more keywords
Blood transcriptome and clonal T-cell correlates of response and non-response to eltrombopag therapy in a cohort of patients with chronic immune thrombocytopenia
Sign Up to like & getrecommendations! Published in 2019 at "Haematologica"
DOI: 10.3324/haematol.2019.226688
Abstract: Immune thrombocytopenia (ITP) is an autoimmune disease characterized by a low platelet count caused by accelerated platelet destruction and/or impaired platelet production. Chronic ITP is defined as ITP lasting for more than 12 months.[1][1] T-cell… read more here.
Keywords: transcriptome clonal; response; blood transcriptome; immune thrombocytopenia ... See more keywords
Blood transcriptome reveals immune and metabolic-related genes involved in growth of pasteurized colostrum-fed calves
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1075950
Abstract: The quality of colostrum is a key factor contributing to healthy calf growth, and pasteurization of colostrum can effectively reduce the counts of pathogenic microorganisms present in the colostrum. Physiological changes in calves fed with… read more here.
Keywords: colostrum; growth pasteurized; immune metabolic; pasteurized colostrum ... See more keywords
Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Leishmania infantum Infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.784463
Abstract: Visceral leishmaniasis (VL) is a vector-borne infectious disease that can be potentially fatal if left untreated. In Brazil, it is caused by Leishmania infantum parasites. Blood transcriptomics allows us to assess the molecular mechanisms involved… read more here.
Keywords: leishmania infantum; mrna coexpression; long noncoding; blood ... See more keywords
Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene
Sign Up to like & getrecommendations! Published in 2022 at "Non-Coding RNA"
DOI: 10.3390/ncrna8020024
Abstract: Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long non-coding RNAs to combat invading… read more here.
Keywords: receptor gene; c5a; non coding; complement ... See more keywords