Blood transcriptomic biomarker as a surrogate of ischemic brain gene expression
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50861
Abstract: Blood biomarkers for cerebral tissue ischemia are lacking. The goal was to identify a blood transcriptomic signature jointly identified in the ischemic brain. read more here.
Keywords: biomarker surrogate; blood transcriptomic; blood; ischemic brain ... See more keywords
Whole blood transcriptomic profiling identifies molecular pathways related to cardiovascular mortality in heart failure
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2540
Abstract: Chronic heart failure (CHF) is a systemic syndrome with a poor prognosis and a need for novel therapies. We investigated whether whole blood transcriptomic profiling can provide new mechanistic insights into cardiovascular (CV) mortality in… read more here.
Keywords: blood transcriptomic; heart failure; transcriptomic profiling; whole blood ... See more keywords
Whole blood transcriptomic investigation identifies long non-coding RNAs as regulators in sepsis
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DOI: 10.1186/s12967-020-02372-2
Abstract: Background Sepsis is a fatal disease referring to the presence of a known or strongly suspected infection coupled with systemic and uncontrolled immune activation causing multiple organ failure. However, current knowledge of the role of lncRNAs… read more here.
Keywords: sepsis; blood transcriptomic; transcriptomic investigation; whole blood ... See more keywords
Systematic review of diagnostic and prognostic host blood transcriptomic signatures of tuberculosis disease in people living with HIV
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DOI: 10.12688/gatesopenres.14327.2
Abstract: Background HIV-associated tuberculosis (TB) has high mortality; however, current triage and prognostic tools offer poor sensitivity and specificity, respectively. We conducted a systematic review of diagnostic and prognostic host-blood transcriptomic signatures of TB in people… read more here.
Keywords: host blood; blood transcriptomic; transcriptomic signatures; systematic review ... See more keywords