Conditioning regimen with a 75% dose of standard busulfan/cyclophosphamide plus fludarabine before cord blood transplantation in older patients with AML and MDS
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Hematology"
DOI: 10.1007/s12185-019-02688-w
Abstract: In this retrospective study, we aimed to establish a conditioning regimen for older patients receiving cord blood transplantation (CBT). This study included 21 older patients [median age 65 (58–73) years] with acute myeloid leukemia and myelodysplastic… read more here.
Keywords: older patients; cord blood; conditioning regimen; blood transplantation ... See more keywords
Reactivation of BK virus after double umbilical cord blood transplantation in adults correlates with impaired reconstitution of CD4+ and CD8+ T effector memory cells and increase of T regulatory cells.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical immunology"
DOI: 10.1016/j.clim.2019.06.010
Abstract: BK virus (BKV), a human polyomavirus that remains latent in renal epithelial cells, can be reactivated after hematopoietic stem cell transplantation (HSCT) leading to hemorrhagic cystitis. The incidence of BK viremia is higher after Umbilical… read more here.
Keywords: cd8; cord blood; umbilical cord; reconstitution ... See more keywords
Cord blood transplantation: rewind to fast forward
Sign Up to like & getrecommendations! Published in 2017 at "Bone Marrow Transplantation"
DOI: 10.1038/bmt.2016.336
Abstract: The utilization of cord blood as a source of stem cells for transplantation has decreased in recent years. Although cord blood transplantation (CBT) is an established practice for the treatment of adult and pediatric patients… read more here.
Keywords: transplantation; blood transplantation; cord blood; cbt ... See more keywords
Retrospective cohort study comparing the outcomes of intravenous busulfan vs. total-body irradiation after single cord blood transplantation
Sign Up to like & getrecommendations! Published in 2019 at "Bone Marrow Transplantation"
DOI: 10.1038/s41409-019-0441-4
Abstract: Limited to inadequate stem-cell doses, cord blood transplantation (UCBT) is accompanied by increased graft failure and delayed haematopoietic recovery. The conditioning regimen is critically important for engraftment, and numerous trials have been undertaken comparing the… read more here.
Keywords: cohort; transplantation; blood transplantation; cord blood ... See more keywords
Cord blood transplantation for acute leukemia
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2020.1782380
Abstract: ABSTRACT Introduction Umbilical cord blood transplantation (UCBT) is a suitable alternative for patients with acute leukemia (AL) in need of an allograft and who lack an HLA-matched donor. Single-institution and registry studies have shown that,… read more here.
Keywords: acute leukemia; blood transplantation; cord blood;
Umbilical Cord Blood Transplantation: Connecting Its Origin to Its Future
Sign Up to like & getrecommendations! Published in 2023 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szac086
Abstract: Abstract Transplantation of umbilical cord blood (UCB) is an attractive alternative source of hematopoietic stem cells (HSCs). The unique properties of cord blood and its distinct immune tolerance and engraftment kinetics compared to bone marrow… read more here.
Keywords: blood; blood transplantation; umbilical cord; cord blood ... See more keywords
Gemtuzumab Ozogamicin Followed by Unrelated Cord Blood Transplantation With Reduced-intensity Conditioning for a Child With Refractory Acute Promyelocytic Leukemia.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pediatric hematology/oncology"
DOI: 10.1097/mph.0000000000002404
Abstract: There is no established treatment for patients with acute promyelocytic leukemia (APL) refractory to targeted therapies with all-trans retinoic acid (ATRA) and/or arsenic trioxide (ATO). We report here a case of an 8-month-old girl with… read more here.
Keywords: blood transplantation; gemtuzumab ozogamicin; promyelocytic leukemia; unrelated cord ... See more keywords
Cord Blood Transplantation in 2 Infants Presenting Monosomy 7 Clonal Hematopoiesis; SAMD9/SAMD9L Germline Mutation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pediatric hematology/oncology"
DOI: 10.1097/mph.0000000000002578
Abstract: Recently, germline mutations in SAMD9 and SAMD9L were increasingly found in children with monosomy 7. We report the outcomes in 2 infants with the SAMD9/SAMD9L variant, who presented with anemia and thrombocytopenia (patient 1), and… read more here.
Keywords: blood transplantation; samd9 samd9l; cord blood;
Cord blood transplantation in a patient with severe motor and intellectual disabilities and myelodysplastic syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Pediatrics International"
DOI: 10.1111/ped.14260
Abstract: pathogenetic implications of oral fibrinolysis on bleeding. Experimental and clinical studies of the haemostatic balance in the oral cavity, with particular reference to patients with acquired and congenital defec. Dan. Med. Bull. 1991; 38: 427–… read more here.
Keywords: severe motor; transplantation patient; cord blood; blood ... See more keywords
Clinical outcome of cord blood transplantation for nine children with juvenile myelomonocytic leukemia receiving fludarabine-busulfan-cyclophosphamide-based conditioning.
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric transplantation"
DOI: 10.1111/petr.14181
Abstract: BACKGROUND Juvenile myelomonocytic leukemia (JMML) is a rare hematological malignancy in young children and can only be cured through the allogeneic stem cell transplantation. PROCEDURE We have retrospectively analyzed the outcomes of nine children with… read more here.
Keywords: juvenile myelomonocytic; nine children; cord blood; transplantation ... See more keywords
Early and late outcomes after cord blood transplantation for pediatric patients with inherited leukodystrophies.
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DOI: 10.1182/bloodadvances.2017010645
Abstract: Leukodystrophies (LD) are devastating inherited disorders leading to rapid neurological deterioration and premature death. Hematopoietic stem cell transplantation (HSCT) can halt disease progression for selected LD. Cord blood is a common donor source for transplantation… read more here.
Keywords: cord blood; transplantation; blood; blood transplantation ... See more keywords