Coomassie brilliant blue G-250 acts as a potential chemical chaperone to stabilize therapeutic insulin
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DOI: 10.1039/d3cc01791e
Abstract: Our studies show Coomassie Brilliant Blue G-250 as a promising chemical chaperone that stabilises the α-helical native human insulin conformers, disrupting their aggregation. Furthermore, it also increases the insulin secretion. This multipolar effect coupled with… read more here.
Keywords: chemical chaperone; blue 250; coomassie brilliant; chemical ... See more keywords