Human Blue Cone Opsin Regeneration Involves Secondary Retinal Binding with Analog Specificity.
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical journal"
DOI: 10.1016/j.bpj.2018.01.032
Abstract: Human color vision is mediated by the red, green, and blue cone visual pigments. Cone opsins are G-protein-coupled receptors consisting of an opsin apoprotein covalently linked to the 11-cis-retinal chromophore. All visual pigments share a… read more here.
Keywords: blue cone; cone; cone opsin; regeneration ... See more keywords
The landscape of submicroscopic structural variants at the OPN1LW/OPN1MW gene cluster on Xq28 underlying blue cone monochromacy
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2115538119
Abstract: Significance Blue cone monochromacy (BCM) is an inherited retinal disorder characterized by low vision and poor color vision and caused by mutations in the multicopy gene cluster encoding the long- and middle-wavelength-sensitive cone photoreceptor visual… read more here.
Keywords: cone monochromacy; gene; blue cone; gene cluster ... See more keywords
Foveal Therapy in Blue Cone Monochromacy: Predictions of Visual Potential From Artificial Intelligence
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2020.00800
Abstract: Novel therapeutic approaches for treating inherited retinal degenerations (IRDs) prompt a need to understand which patients with impaired vision have the anatomical potential to gain from participation in a clinical trial. We used supervised machine… read more here.
Keywords: machine; machine learning; bcm; structure ... See more keywords