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Published in 2020 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2020.04.004
Abstract: Halophilic Halomonas bluephagenesis (H. bluephagenesis), a chassis for cost-effective Next Generation Industrial Biotechnology (NGIB), was for the first time engineered to successfully produce L-threonine, one of the aspartic family amino acids (AFAAs). Five exogenous genes…
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Keywords:
production;
halomonas bluephagenesis;
bluephagenesis;
threonine ... See more keywords
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Published in 2022 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2022.04.001
Abstract: Polyhydroxyalkanoates (PHA) are a family of biodegradable and biocompatible plastics with potential to replace petroleum based plastics. Diversity of PHA monomer structures provides flexibility in material properties to suit more applications. In this study, 5-hydroxyvalerate…
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Keywords:
bluephagenesis;
derived polyhydroxyalkanoates;
4hb 5hv;
biosynthesis diverse ... See more keywords
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Published in 2021 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00320
Abstract: Itaconic acid (IA), an important five-carbon unsaturated dicarboxylic acid, is one of the top 12 renewable chemicals with an urgent need to reduce industrial production costs. Halomonas bluephagenesis, which possesses the potential for cost-effective bioproduction…
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Keywords:
halomonas bluephagenesis;
bluephagenesis;
citrate;
cell catalysis ... See more keywords
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Published in 2022 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.13999
Abstract: Bacterial outer membrane (OM) is a self‐protective and permeable barrier, while having many non‐negligible negative effects in industrial biotechnology. Our previous studies revealed enhanced properties of Halomonas bluephagenesis based on positive cellular properties by OM…
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Keywords:
bluephagenesis;
hyperproduction pha;
halomonas bluephagenesis;
outer membrane ... See more keywords
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Published in 2022 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.14158
Abstract: Halomonas bluephagenesis TD1.0 was engineered to produce the biofuel propane, bioplastic poly‐3‐hydroxybutyrate (PHB), and biochemicals mandelate and hydroxymandelate in a single, semi‐continuous batch fermentation under non‐sterile conditions. Multi‐product separation was achieved by segregation of the…
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Keywords:
bluephagenesis;
halomonas bluephagenesis;
biofuel bioplastics;
production biofuel ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27093022
Abstract: Acetate is a promising economical and sustainable carbon source for bioproduction, but it is also a known cell-growth inhibitor. In this study, adaptive laboratory evolution (ALE) with acetate as selective pressure was applied to Halomonas…
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Keywords:
adaptive laboratory;
bluephagenesis;
halomonas bluephagenesis;
phb ... See more keywords