BILIVERDIN REDUCTASE B/ FLAVIN REDUCTASE (BLVRB/FLR) EXHIBITS HEME-REGULATED, NADPH-DEPENDENT REDUCTASE ACTIVITY AND CONFERS CYTOPROTECTION IN DEVELOPING ERYTHROID CELLS
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DOI: 10.1016/j.exphem.2019.06.400
Abstract: Biliverdin reductase B (BLVRB), also known as flavin reductase (FLR), is especially expressed in cells having high levels of heme synthesis (e.g. developing erythroid cells, fetal and adult liver). BLVRB exhibits NADPH-dependent reductase activity toward… read more here.
Keywords: heme; nadph dependent; developing erythroid; blvrb ... See more keywords
Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis
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DOI: 10.3390/biom13060882
Abstract: Background: Intraplaque hemorrhage (IPH) is a hallmark of atherosclerotic plaque instability. Biliverdin reductase B (BLVRB) is enriched in plasma and plaques from patients with symptomatic carotid atherosclerosis and functionally associated with IPH. Objective: We explored… read more here.
Keywords: patients symptomatic; blvrb; ischemic stroke; plasma blvrb ... See more keywords