Chronic Kidney Disease Is Associated With Greater Bone Marrow Adiposity
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DOI: 10.1002/jbmr.3562
Abstract: Bone marrow adiposity is associated with aging, osteoporosis, and reduced hematopoiesis, as well as anorexia nervosa, but little is known about the underlying mechanisms that affect marrow adiposity. Chronic kidney disease (CKD) may influence bone… read more here.
Keywords: bmat; bone; marrow adiposity; bone marrow ... See more keywords
Sclerostin‐Neutralizing Antibody Treatment Rescues Negative Effects of Rosiglitazone on Mouse Bone Parameters
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DOI: 10.1002/jbmr.4170
Abstract: Obesity, a growing pandemic, is a risk factor for many cancers and causes increased bone marrow adipose tissue (BMAT). in vitro studies and obese animal models suggest that BMAT contributes to cancer progression, but there… read more here.
Keywords: sclerostin neutralizing; neutralizing antibody; bmat; bone ... See more keywords
Saturated and Unsaturated Bone Marrow Lipids Have Distinct Effects on Bone Density and Fracture Risk in Older Adults
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4504
Abstract: Greater bone marrow adiposity (BMAT) is associated with lower bone mineral density (BMD) and vertebral fractures; less is known about BMAT composition and bone. We studied BMAT composition and bone outcomes in 465 participants from… read more here.
Keywords: fracture; saturation; bone; marrow ... See more keywords
Bone Marrow Adiposity in Models of Radiation‐ and Aging‐Related Bone Loss Is Dependent on Cellular Senescence
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DOI: 10.1002/jbmr.4537
Abstract: Oxidative stress‐induced reactive oxygen species, DNA damage, apoptosis, and cellular senescence have been associated with reduced osteoprogenitors in a reciprocal fashion to bone marrow adipocyte tissue (BMAT); however, a direct (causal) link between cellular senescence… read more here.
Keywords: bone marrow; bone; bmat; bone loss ... See more keywords
The accurate relationship between spine bone density and bone marrow in humans.
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DOI: 10.1016/j.bone.2020.115312
Abstract: CONTEXT The accuracy of QCT measurements of lumbar spine trabecular volumetric bone mineral density (vBMD) is decreased due to differences in the amount of bone marrow adipose tissue (BMAT). OBJECTIVE To correct vBMD measurements for… read more here.
Keywords: vbmd; bmat; bone; relationship ... See more keywords
Vertebrae but not femur marrow fat transiently decreases in response to body weight loss in an 18-month randomized control trial.
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DOI: 10.2139/ssrn.4290888
Abstract: BACKGROUND Increased levels of bone marrow adipose tissue (BMAT) are negatively associated with skeletal health and hematopoiesis. BMAT is known to increase with age; however, the effect of long-term weight loss on BMAT is still… read more here.
Keywords: marrow; fat depots; age; bmat ... See more keywords
PiT2 deficiency prevents increase of bone marrow adipose tissue during skeletal maturation but not in OVX-induced osteoporosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.921073
Abstract: The common cellular origin between bone marrow adipocytes (BMAds) and osteoblasts contributes to the intimate link between bone marrow adipose tissue (BMAT) and skeletal health. An imbalance between the differentiation ability of BMSCs towards one… read more here.
Keywords: bone marrow; bone; bmat; pit2 ... See more keywords