Articles with "bmdm" as a keyword



PGE2-PKA Control of Mitochondrial Membrane Potential Dictates Macrophages Proliferation and Efferocytic Function During Lung Injury

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Published in 2024 at "Physiology"

DOI: 10.1152/physiol.2024.39.s1.2190

Abstract: In the lungs, phenotypically different alveolar macrophages (AMs) co-exist with interstitial monocyte-derived macrophages (Mo-Macs) to regulate lung homeostasis. We have shown that airspace-recruited Mo-Macs resolve inflammation, restoring lung-fluid homeostasis. Analyzing publicly available datasets (Immgen Consortium),… read more here.

Keywords: lung; pge2; physiology; function ... See more keywords

Clonorchis sinensis extracellular vesicles associated with Csi-let-7a-5p activate pro-inflammatory macrophages to induce biliary injury

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Published in 2025 at "PLOS Neglected Tropical Diseases"

DOI: 10.1371/journal.pntd.0013080

Abstract: During Clonorchis sinensis (C. sinensis) infection, pro-inflammatory macrophages (M1 macrophages) are highly activated, yet their role in the disease remains poorly understood. Previous studies have demonstrated that extracellular vesicles from C. sinensis (CsEVs) can activate… read more here.

Keywords: csi let; sinensis; pro inflammatory; inflammatory macrophages ... See more keywords

A Role for Macrophage Adenosine 2A Receptor in Diet-Induced Nonalcoholic Fatty Liver Disease

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Published in 2018 at "Diabetes"

DOI: 10.2337/db18-1872-p

Abstract: Recent evidence suggests that adenosine 2A receptor (A2AR) exerts a protective role in NAFLD. However, the role of the A2AR in macrophages in NAFLD pathophysiology remains unknown. In the present study, hepatic inflammation and fat… read more here.

Keywords: adenosine receptor; bmdm; role; macrophage ... See more keywords

The influence of high glucose conditions on macrophages and its effect on the autophagy pathway

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1130662

Abstract: Introduction Macrophages are central cells in mediating the inflammatory response. Objective and Methods We evaluated the effect of high glucose conditions on the inflammatory profile and the autophagy pathway in Bone-Marrow Derived Macrophages (BMDM) from… read more here.

Keywords: glucose conditions; effect; high glucose; autophagy pathway ... See more keywords