Bovine Mucosal Heparins Are Comparable to Porcine Mucosal Heparin at USP Potency Adjusted Levels
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2018.00360
Abstract: Introduction: Bovine mucosal heparins (BMH) are currently being developed for re-introduction for both medical and surgical indications. BMH active pharmaceutical ingredient (API) exhibits a somewhat weaker USP potency when compared to PMHs. We hypothesized that… read more here.
Keywords: heparin; pmh; potency; usp potency ... See more keywords
RNA Polymerase I Is Uniquely Vulnerable to the Small-Molecule Inhibitor BMH-21
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14225544
Abstract: Simple Summary Cancer cells upregulate RNA polymerase I (Pol I) activity to increase ribosome abundance in support of rapid cell growth and proliferation. During the last decade, Pol I has emerged as a promising anti-cancer… read more here.
Keywords: bmh; cancer; rna polymerase; pol ... See more keywords