Human embryonic stem cell-derived mesenchymal stem cell secretome reverts silica-induced airway epithelial cell injury by regulating Bmi1 signaling.
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DOI: 10.1002/tox.23833
Abstract: Silicosis is an irreversible chronic pulmonary disease caused by long-term inhalation and deposition of silica particles, which is currently incurable. The exhaustion of airway epithelial stem cells plays a pathogenetic role in silicosis. In present… read more here.
Keywords: cell; bmi1 signaling; stem cell; airway epithelial ... See more keywords