SLAP Is a Negative Regulator of FcεRI Receptor-Mediated Signaling and Allergic Response
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DOI: 10.3389/fimmu.2019.01020
Abstract: Binding of antigen to IgE-high affinity FcεRI complexes on mast cells and basophils results in the release of preformed mediators such as histamine and de novo synthesis of cytokines causing allergic reactions. Src-like adapter protein… read more here.
Keywords: cell; response; slap; bmmcs ... See more keywords
Kaempferol Suppresses the Activation of Mast Cells by Modulating the Expression of FcεRI and SHIP1
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DOI: 10.3390/ijms24065997
Abstract: In the present study, we evaluated the effects of kaempferol on bone marrow-derived mast cells (BMMCs). Kaempferol treatment significantly and dose-dependently inhibited IgE-induced degranulation, and cytokine production of BMMCs under the condition that cell viability… read more here.
Keywords: kaempferol; ship1; expression; bmmcs ... See more keywords