Youthful Stem Cell Microenvironments: Rejuvenating Aged Bone Repair Through Mitochondrial Homeostasis Remodeling
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DOI: 10.1002/advs.202409644
Abstract: Extracellular matrix (ECM) derived from mesenchymal stem cells regulates antioxidant properties and bone metabolism by providing a favorable extracellular microenvironment. However, its functional role and molecular mechanism in mitochondrial function regulation and aged bone regeneration… read more here.
Keywords: bmmscs; homeostasis; stem; bone ... See more keywords
Preconditioning with melatonin improves therapeutic outcomes of bone marrow-derived mesenchymal stem cells in targeting liver fibrosis induced by CCl4
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DOI: 10.1007/s00441-017-2604-1
Abstract: Preconditioning of mesenchymal stem cells (MSCs) with melatonin (MT) has shown promising results in animal models of myocardial infarction, renal ischemia and cerebral ischemia. Here, we use this strategy in the liver fibrosis induced by… read more here.
Keywords: liver fibrosis; bmmscs; ccl4; fibrosis induced ... See more keywords
Improvement in viability and mineralization of osteoporotic bone marrow mesenchymal stem cell through combined application of photobiomodulation therapy and oxytocin
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DOI: 10.1007/s10103-019-02848-8
Abstract: The probable positive effects of photobiomodulation therapy (PBMT) and oxytocin (OT) treatments together or alone were evaluated on cell viability along with the changes in the gene expression of Osteocalcin (OC), Osteoprotegerin (OPG), and Runt-related… read more here.
Keywords: osteogenic induction; viability; ovx bmmsc; pbmt ... See more keywords
Melatonin preconditioning of bone marrow-derived mesenchymal stem cells promotes their engraftment and improves renal regeneration in a rat model of chronic kidney disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Histology"
DOI: 10.1007/s10735-019-09812-4
Abstract: Bone marrow-derived mesenchymal stem cells (BMMSCs) transplantation has shown to be effective in treating chronic kidney disease. However, the effectiveness of this strategy is constrained by low homing and survival rate of transplanted cells in… read more here.
Keywords: marrow derived; kidney; bmmscs; uuo bmmscs ... See more keywords
Pretreatment with Bisphosphonate Enhances Osteogenesis of Bone Marrow Mesenchymal Stem Cells.
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DOI: 10.1089/scd.2016.0173
Abstract: Mesenchymal stem cell (MSC)-mediated bone regeneration is used to replace lost bone. However, methods to accelerate the process and stabilize regenerated bone remain limited. Therefore, we investigated the effect of bisphosphonates (BPs) on the function… read more here.
Keywords: bmmscs; bone; osteogenesis; stem cells ... See more keywords
Melatonin Improves the Resistance of Oxidative Stress-Induced Cellular Senescence in Osteoporotic Bone Marrow Mesenchymal Stem Cells
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DOI: 10.1155/2022/7420726
Abstract: Accumulation of senescent bone marrow-derived mesenchymal stem cells (BMMSCs) has led to an age-related bone loss. However, the role of stem cell senescence in estrogen deficiency-induced osteoporosis remains elusive. Though melatonin plays a vital role… read more here.
Keywords: bone; bmmscs; senescence; stem cells ... See more keywords
Intestinal Microbiota Participates in the Protective Effect of HO-1/BMMSCs on Liver Transplantation With Steatotic Liver Grafts in Rats
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DOI: 10.3389/fmicb.2022.905567
Abstract: The present study aimed to explore whether heme oxygenase-1 (HO-1)-modified bone marrow mesenchymal stem cells (BMMSCs) have a protective effect on liver transplantation with steatotic liver grafts in rats, and to determine the role of… read more here.
Keywords: steatotic liver; liver; intestinal microbiota; effect ... See more keywords
Effect of CXCR3/HO-1 genes modified bone marrow mesenchymal stem cells on small bowel transplant rejection
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DOI: 10.3748/wjg.v23.i22.4016
Abstract: AIM To investigate whether bone marrow mesenchymal stem cells (BMMSCs) modified with the HO-1 and CXCR3 genes can augment the inhibitory effect of BMMSCs on small bowel transplant rejection. METHODS Lewis rat BMMSCs were cultured… read more here.
Keywords: small bowel; bowel; bowel transplant; cxcr3 genes ... See more keywords