Structural basis of BMP‐2 and BMP‐7 interactions with antagonists Gremlin‐1 and Noggin in Glioblastoma tumors
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DOI: 10.1002/jcc.26407
Abstract: In Glioblastoma (GBM) brain tumors, both Gremlin‐1 and Noggin are reported to bind to BMP and inhibit BMP‐signaling, thereby allowing the cell to maintain tumorous morphology. Enlisting the interfacial residues important for protein–protein complex formation… read more here.
Keywords: structural basis; bmp; gremlin noggin; glioblastoma ... See more keywords
IMBALANCE IN BONE MORPHOGENIC PROTEINS 2 AND 7 IS ASSOCIATED WITH HYPERTENSION AND ARTERIAL STIFFNESS IN CHRONIC KIDNEY DISEASE
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000835992.77414.e5
Abstract: Objective: Patients with chronic kidney disease (CKD) exhibit an elevated cardiovascular risk from the early stages (I-III) with an exponentially increasing risk of cardiovascular death as kidney function worsens. The hypothesis of this study is… read more here.
Keywords: hypertension; kidney; bmp; bmp bmp ... See more keywords
Morphologic and molecular alteration during tibia fracture healing in rat.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201803_14463
Abstract: OBJECTIVE To monitor morphological feature and related osteogenic and bone metabolic change during healing of tibia fracture in a rat model. MATERIALS AND METHODS Tibia density and trabecular thickness were evaluated. Histopathology was examined by… read more here.
Keywords: week; fracture; tibia fracture; fracture healing ... See more keywords
Imbalance in Bone Morphogenic Proteins 2 and 7 Is Associated with Renal and Cardiovascular Damage in Chronic Kidney Disease
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DOI: 10.3390/ijms24010040
Abstract: Arterial stiffness is a major vascular complication of chronic kidney disease (CKD). The development of renal damage, hypertension, and increased pulse wave velocity (PWV) in CKD might be associated with an imbalance in bone morphogenetic… read more here.
Keywords: damage; kidney; bmp; imbalance ... See more keywords
The correlation of the BMP-4 and BMP-7 proteins of the TGFβ-BMP-SMAD pathway in the response to a specific and non-specific trigger in asthma.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in respiratory medicine"
DOI: 10.5603/arm.87955
Abstract: INTRODUCTION Asthma is characterized by persistent inflammation, airway hypersensitivity and remodelling. Bone Morphogenetic Proteins belong to the Transforming Growth Factor Superfamily and have a similar signalling transduction pathway and common co-mediating protein. However, the BMPs… read more here.
Keywords: correlation bmp; bmp bmp; bmp; bmp proteins ... See more keywords