Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis.
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DOI: 10.1002/jper.20-0354
Abstract: BACKGROUND Periodontitis is caused by multiple factors involving a bacterial challenge and a susceptible host, although there is no report on gene mutation directly linked to this common disease. Mutations in the proteinase bone morphogenetic… read more here.
Keywords: periodontal homeostasis; proteinase bone; bmp1 tll1;
BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Dental Research"
DOI: 10.1177/0022034516686558
Abstract: Mutations in bone morphogenetic protein 1 (BMP1) in humans or deletion of BMP1 and related protease tolloid like 1 (TLL1) in mice lead to osteogenesis imperfecta (OI). Here, we show progressive periodontal defects in mice… read more here.
Keywords: homeostasis; bmp1 tll1; alveolar bone; periodontal homeostasis ... See more keywords