Optimized expression and purification of a soluble BMP2 variant based on in-silico design.
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DOI: 10.1016/j.pep.2021.105918
Abstract: Bone morphogenetic protein 2 (BMP21) is a highly interesting therapeutic growth factor due to its strong osteogenic/osteoinductive potential. However, its pronounced aggregation tendency renders recombinant and soluble production troublesome and complex. While prokaryotic expression systems… read more here.
Keywords: bmp2; bmp2 2hep; expression; bmp2 variant ... See more keywords