Targeted Delivery of Exosomal Bmp2 mRNA via a Bioadhesive Interface Synergistically Enhances Titanium Implant Osseointegration.
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DOI: 10.1002/smll.202510386
Abstract: Rapid osseointegration of titanium implants remains challenging under pathological conditions. This study develops an engineered exosome-based mRNA delivery system for osteogenic regulation. Through co-transfection with BMP2 and Paip2 plasmids, Exosomes (Exoen) loaded with untranslated Bmp2 mRNA are… read more here.
Keywords: titanium; mrna; bmp2 mrna; delivery ... See more keywords