BMP9 knockout impairs pulmonary vessel muscularisation and confers aberrant tamoxifen sensitivity
Sign Up to like & getrecommendations! Published in 2025 at "Angiogenesis"
DOI: 10.1007/s10456-025-10017-5
Abstract: Deleterious mutations in the GDF2 gene, encoding BMP9, are causative of pulmonary arterial hypertension and hereditary haemorrhagic telangiectasia. Paradoxically, BMP9 germ-line knockout (Gdf2−/−; Bmp9 KO) and double Bmp9 KO/conditional Bmp10 cKO (dKO) mice exhibit an… read more here.
Keywords: mice; dko mice; bmp9 knockout; vessel ... See more keywords
Comparison of the biomechanical differences in the occlusal movement of wild-type and BMP9 knockout mice with apical periodontitis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1036061
Abstract: Apical periodontitis is a common clinical disease caused by bacteria; bacterial metabolites can cause an imbalance in bone homeostasis, bone mass reduction, and tooth loss. Bone resorption in apical periodontitis causes a concentration of stress… read more here.
Keywords: stress; apical periodontitis; bone; bmp9 knockout ... See more keywords