Physiologically‐based pharmacokinetic modelling of a CYP2C19 substrate, BMS‐823778, utilizing pharmacogenetic data
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DOI: 10.1111/bcp.13565
Abstract: Previous studies demonstrated direct correlation between CYP2C19 genotype and BMS‐823778 clearance in healthy volunteers. The objective of the present study was to develop a physiologically‐based pharmacokinetic (PBPK) model for BMS‐823778 and use the model to… read more here.
Keywords: based pharmacokinetic; pharmacokinetic modelling; bms 823778; physiologically based ... See more keywords