BMSC-Derived Exosomal CircHIPK3 Promotes Osteogenic Differentiation of MC3T3-E1 Cells via Mitophagy
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DOI: 10.3390/ijms24032785
Abstract: Exosome-based therapy is emerging as a promising strategy to promote bone regeneration due to exosomal bioactive cargos, among which circular RNA (circRNA) has recently been recognized as the key effector. The role of exosomal circRNA… read more here.
Keywords: derived exosomal; bmsc derived; differentiation; mc3t3 ... See more keywords
Effects of BMSC-Derived EVs on Bone Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14051012
Abstract: Extracellular vesicles (EVs) are small membrane vesicles that can be secreted by most cells. EVs can be released into the extracellular environment through exocytosis, transporting endogenous cargo (proteins, lipids, RNAs, etc.) to target cells and… read more here.
Keywords: effects bmsc; bmsc derived; bone; bmsc evs ... See more keywords
Bone marrow mesenchymal stem cell-derived exosomal microRNAs target PI3K/Akt signaling pathway to promote the activation of fibroblasts
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DOI: 10.4252/wjsc.v15.i4.248
Abstract: BACKGROUND Fibroblast plays a major role in tendon-bone healing. Exosomes derived from bone marrow mesenchymal stem cells (BMSCs) can activate fibroblasts and promote tendon-bone healing via the contained microRNAs (miRNAs). However, the underlying mechanism is… read more here.
Keywords: pi3k akt; derived exosomal; bmsc derived; bone ... See more keywords
Comparison of the Effects of BMSC-derived Schwann Cells and Autologous Schwann Cells on Remyelination Using a Rat Sciatic Nerve Defect Model
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DOI: 10.7150/ijbs.26765
Abstract: Schwann cells (SCs) are primarily responsible for the formation of myelin sheaths, yet bone marrow mesenchymal stem cell (BMSC)-derived SCs are often used to replace autologous SCs and assist with the repair of peripheral nerve… read more here.
Keywords: seed; schwann cells; remyelination; nerve ... See more keywords
Bone marrow mesenchymal stem cell-derived exosomes protect podocytes from HBx-induced ferroptosis
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DOI: 10.7717/peerj.15314
Abstract: Introduction Hepatitis B virus-associated glomerulonephritis (HBV-GN) is a common secondary kidney disease in China, the pathogenesis of which is not completely clear, and there is still a lack of effective treatment. Methods The mechanism of… read more here.
Keywords: derived exosomes; bmsc derived; bone marrow; mir 223 ... See more keywords