Articles with "bmsc exos" as a keyword



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Exosomes derived from bone marrow mesenchymal stem cells promote osteosarcoma development by activating oncogenic autophagy

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Published in 2020 at "Journal of Bone Oncology"

DOI: 10.1016/j.jbo.2020.100280

Abstract: Highlights • BMSC-Exos promote malignant tumorigenesis and metastasis in OS cells.• BMSC-Exos promotes oncogenic autophagy in OS cells.• BMSC-Exos-mediated autophagy contributes to the BMSC-Exos-induced malignant tumorigenesis metastasis in OS cells. read more here.

Keywords: derived bone; exosomes derived; bmsc exos; autophagy ... See more keywords
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Bone marrow mesenchymal stem cell-derived exosomes alleviate peritoneal dialysis-associated peritoneal injury.

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Published in 2023 at "Stem cells and development"

DOI: 10.1089/scd.2022.0244

Abstract: Peritoneal fibrosis is a critical sequela that limits the application of peritoneal dialysis (PD). This study explored the role and mechanism of bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos) in preventing PD-associated peritoneal injury. C57BL/6… read more here.

Keywords: cell; peritoneal dialysis; peritoneal injury; stem ... See more keywords
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Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology

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Published in 2022 at "Journal of Neuroinflammation"

DOI: 10.1186/s12974-022-02393-2

Abstract: Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal stem cells (BMSC-exos) are extracellular vesicles that can execute the function of bone-marrow mesenchymal… read more here.

Keywords: bdnf; expression; bmsc exos; test ... See more keywords

Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Promote Angiogenesis in Ischemic Stroke Mice via Upregulation of MiR-21-5p

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12070883

Abstract: Exosomes derived from bone mesenchymal stem cells (BMSC-Exos) are one of the main factors responsible for the therapeutic effects of BMSCs. The study aimed to investigate whether BMSC-Exos could promote angiogenesis in ischemic stroke mice… read more here.

Keywords: bmsc exos; stroke mice; ischemic stroke; promote angiogenesis ... See more keywords

PF127 Hydrogel-Based Delivery of Exosomal CTNNB1 from Mesenchymal Stem Cells Induces Osteogenic Differentiation during the Repair of Alveolar Bone Defects

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Published in 2023 at "Nanomaterials"

DOI: 10.3390/nano13061083

Abstract: Pluronic F127 (PF127) hydrogel has been highlighted as a promising biomaterial for bone regeneration, but the specific molecular mechanism remains largely unknown. Herein, we addressed this issue in a temperature-responsive PF127 hydrogel loaded with bone… read more here.

Keywords: alveolar bone; bone; osteogenic differentiation; pf127 hydrogel ... See more keywords
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Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways

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Published in 2021 at "Asian Journal of Andrology"

DOI: 10.4103/aja.aja_98_20

Abstract: Spermatogenic dysfunction caused by cyclophosphamide (CP) chemotherapy has seriously influenced the life quality of patients. Unfortunately, treatments for CP-induced testicular spermatogenic dysfunction are limited, and the molecular mechanisms are not fully understood. For the first… read more here.

Keywords: reproductive toxicity; erk akt; bmsc exos; p38mapk erk ... See more keywords