Impaired Peyer's patch development in BOB.1/OBF.1‐deficient mice
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DOI: 10.1002/eji.202048578
Abstract: The transcriptional co-activator BOB.1/OBF.1, originally identified in B cells, plays an essential role for the development and function of B and T lymphocytes. The main characteristic of BOB.1/OBF.1-deficient mice is the absence of germinal center… read more here.
Keywords: obf deficient; bob; bob obf; deficient mice ... See more keywords
BOB.1/OBF.1 is required during B‐cell ontogeny for B‐cell differentiation and germinal center function
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202149333
Abstract: BOB.1/OBF.1 is a lymphocyte‐specific transcriptional co‐activator of octamer‐dependent transcription. It regulates the expression of genes important for lymphocyte physiology together with the Oct‐1 and Oct‐2 transcription factors. So far, BOB.1/OBF.1 has been studied in conventional… read more here.
Keywords: bob obf; cell development; cell; germinal center ... See more keywords