Indoloazepinone‐Constrained Oligomers as Cell‐Penetrating and Blood–Brain‐Barrier‐Permeating Compounds
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DOI: 10.1002/cbic.201700678
Abstract: Non‐cationic and amphipathic indoloazepinone‐constrained (Aia) oligomers have been synthesized as new vectors for intracellular delivery. The conformational preferences of the [l‐Aia‐Xxx]n oligomers were investigated by circular dichroism (CD) and NMR spectroscopy. Whereas Boc‐[l‐Aia‐Gly]2,4‐OBn oligomers 12… read more here.
Keywords: blood brain; aia; boc aia; indoloazepinone constrained ... See more keywords