Dual-reagent organophosphine catalyzed asymmetric Mannich reactions of isocyanoacetates with N -Boc-aldimines
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DOI: 10.1016/j.tet.2017.08.031
Abstract: Abstract A combination of an amino-acid derived chiral phosphine catalyst and methyl acrylate has been employed to catalyze the direct Mannich reaction of α-aryl isocyanoacetate and N-Boc-aldimines efficiently. The loading of the catalyst could be… read more here.
Keywords: catalyzed asymmetric; boc aldimines; reagent organophosphine; dual reagent ... See more keywords