Ketone Body Acetoacetate Buffers Methylglyoxal via a Non-enzymatic Conversion during Diabetic and Dietary Ketosis.
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DOI: 10.1016/j.chembiol.2017.07.012
Abstract: The α-oxoaldehyde methylglyoxal is a ubiquitous and highly reactive metabolite known to be involved in aging- and diabetes-related diseases. If not detoxified by the endogenous glyoxalase system, it exerts its detrimental effects primarily by reacting… read more here.
Keywords: body acetoacetate; ketosis; ketone body; non enzymatic ... See more keywords