Structural Inheritance of the Actin Cytoskeletal Organization Determines the Body Axis in Regenerating Hydra.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.01.036
Abstract: Understanding how mechanics complement bio-signaling in defining patterns during morphogenesis is an outstanding challenge. Here, we utilize the multicellular polyp Hydra to investigate the role of the actomyosin cytoskeleton in morphogenesis. We find that the… read more here.
Keywords: body axis; structural inheritance; regenerating hydra; determines body ... See more keywords
Developmental Biology: Reissner’s Fiber and Straightening of the Body Axis
Sign Up to like & getrecommendations! Published in 2018 at "Current Biology"
DOI: 10.1016/j.cub.2018.05.080
Abstract: A straight longitudinal body axis supports efficient directed locomotion of fish and other vertebrates. New research demonstrates that Reissner's fiber, an enigmatic structure within the spinal central canal, is essential for development of an extended trunk… read more here.
Keywords: biology reissner; developmental biology; body axis; biology ... See more keywords
Molecular signature of an ancient organizer regulated by Wnt/β-catenin signalling during primary body axis patterning in Hydra
Sign Up to like & getrecommendations! Published in 2019 at "Communications Biology"
DOI: 10.1038/s42003-019-0680-3
Abstract: Wnt/β-catenin signalling has been shown to play a critical role during head organizer formation in Hydra. Here, we characterized the Wnt signalling regulatory network involved in formation of the head organizer. We found that Wnt… read more here.
Keywords: catenin; catenin signalling; body axis; wnt catenin ... See more keywords
Body-axis organization in tetrapods: a model-system to disentangle the developmental origins of convergent evolution in deep time
Sign Up to like & getrecommendations! Published in 2022 at "Biology Letters"
DOI: 10.1098/rsbl.2022.0047
Abstract: Convergent evolution is a central concept in evolutionary theory but the underlying mechanism has been largely debated since On the Origin of Species. Previous hypotheses predict that developmental constraints make some morphologies more likely to… read more here.
Keywords: model system; convergent evolution; developmental origins; organization ... See more keywords
Neuromesodermal Progenitors: A Basis for Robust Axial Patterning in Development and Evolution
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.607516
Abstract: During early development the vertebrate embryo elongates through a combination of tissue shape change, growth and progenitor cell expansion across multiple regions of the body axis. How these events are coordinated across the length of… read more here.
Keywords: growth; embryo; body axis; neuromesodermal progenitors ... See more keywords
Virtual spherical-shaped multicellular platform for simulating the morphogenetic processes of spider-like body axis formation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.932814
Abstract: Remodeling of multicellular architecture is a critical developmental process for shaping the axis of a bilaterally symmetric animal body and involves coordinated cell–cell interactions and cell rearrangement. In arthropods, the early embryonic process that leads… read more here.
Keywords: cell; platform; axis formation; morphogenetic processes ... See more keywords
Neural induction drives body axis formation during embryogenesis, but a neural induction-like process drives tumorigenesis in postnatal animals
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1092667
Abstract: Characterization of cancer cells and neural stem cells indicates that tumorigenicity and pluripotency are coupled cell properties determined by neural stemness, and tumorigenesis represents a process of progressive loss of original cell identity and gain… read more here.
Keywords: embryogenesis; body axis; process; neural induction ... See more keywords
Studying evolution of the primary body axis in vivo and in vitro
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.69066
Abstract: The metazoan body plan is established during early embryogenesis via collective cell rearrangements and evolutionarily conserved gene networks, as part of a process commonly referred to as gastrulation. While substantial progress has been achieved in… read more here.
Keywords: body; evolution primary; studying evolution; primary body ... See more keywords