Genetic association between RAGE polymorphisms and Alzheimer's disease and Lewy body dementias in a Japanese cohort: a case–control study
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.4600
Abstract: Interaction of receptor for advanced glycation end products (RAGE) with amyloid‐β increases amplification of oxidative stress and plays pathological roles in Alzheimer's disease (AD). Oxidative stress leads to α‐synuclein aggregation and is also a major… read more here.
Keywords: alzheimer disease; lewy body; body dementias;
New Therapeutic Strategies for Lewy Body Dementias
Sign Up to like & getrecommendations! Published in 2017 at "Current Neurology and Neuroscience Reports"
DOI: 10.1007/s11910-017-0778-2
Abstract: This article reviews current treatment strategies and recent advances for the Lewy body dementias (LBDs). Current available symptom treatment strategies are based on monoaminergic, cholinergic and glutaminergic neurotransmitter systems. Relatively robust evidence exists for cholinesterase… read more here.
Keywords: disease; therapeutic strategies; new therapeutic; lewy body ... See more keywords